Dissolution of the (100) face of octacalcium phosphate (OCP) single crystal in weak acidic solutions (pH = 6.5; 25 ̊C) was observed in situ using atomic force microscopy. Monomolecular steps (2.0 nm high) were observed; they originated from etch pits or crystal edges. Advancement of the dissolution process led to precipitation of nanoparticles as small as ~10 nm even though the solution was unde...

The aim of this study was to examine the effect of fluoride ion concentration on the morphology of calcium phosphate crystals grown on acid-etched enamel as a model for tooth enamel erosion. Samples were immersed in calcification solution for 16 h and changes in crystal morphology were monitored by field emission scanning electron microscopy. Without fluoride, plate-like octacalcium phosphate c...

Lesions involving the osteochondral unit are difficult to treat. Biomimetic scaffolds previously shown as promising alternative. Such devices often lack multiple functional layers that mimic bone, cartilage, and interface. In this study, multilayered developed based on use of natural extracellular matrix (ECM)-like biopolymers. Particular attention is paid obtain a complex mimics native transit...

The new heterometallic title complex, [Co(NCS)(2)(C(10)H(8)N(2))(NH(3))(2)][Cr(NCS)(4)(NH(3))(2)]·2CH(3)CN, has been prepared using the open-air reaction of cobalt powder, Reineckes salt and 2,2'-bipyridine (dpy) in acetonitrile. The crystal structure consists of discrete cationic [Co(NCS)(2)(NH(3))(2)(dpy)](+) and anionic [Cr(NCS)(4)(NH(3))(2)](-) building blocks, both with 2 symmetry, and ace...

The spherical porous granules of octacalcium phosphate (OCP) and hydroxyapatite (HA) have the potential for applications in scaffolds bone regeneration. alpha-tricalcium were immersed a pH 5.0 buffer solution that contained 0.1 mM ascorbic acid (AscP), an osteogenesis-promoting drug, at 60 °C. This resulted fabrication AscP-loaded HA/OCP granules. OCP HA phases concentrated surface interior gra...

Octacalcium phosphate (OCP) is widely used in biomaterial fabrication by virtue of its unique crystal structure and low environmental loading. Although various ion molecule substitution methods into the OCP unit lattice have been introduced, it remains unclear which factors mechanisms dominate process. Experimental studies indicated that Na alkali metal ions are substituted at P3 PO4 conjugated...

Calcium phosphate materials have been used increasingly in the past 40 years as bone graft substitutes in the dental and orthopedic fields. Accordingly, numerous fabrication methods have been proposed and used. However, the controlled production of spherical calcium phosphate particles remains a challenge. Since such particles are essential for the synthesis of pastes and cements delivered into...