Ulcerative colitis (UC) is characterized by chronic colonic inflammation, impaired barrier function and gut bacterial dysbiosis. Anthocyanin-containing potatoes have been shown to maintain the intestinal in colitic mice. However, role of microbiota anti-colitic effects anthocyanin-containing not clear. This study evaluated protective efficacy purple- red-fleshed using a DSS-induced murine model...

BACKGROUND: Resistance of microorganisms caused dangerous to human health infections traditional antibiotics is a serious problem for healthcare. In this regard, the development new effective antimicrobial drugs and therapeutic approaches an urgent task. Antimicrobial peptides (AMPs) are considered promising alternative antibiotic in fight against resistant microorganisms.
 AIM: The aim wo...

Phytopathogenic fungi such as the rice blast fungus Magnaporthe grisea are unique in having two catalase/peroxidase (KatG) paralogues located either intracellularly (KatG1) or extracellularly (KatG2). The coding genes have recently been shown to derive from a lateral gene transfer from a (proteo)bacterial genome followed by gene duplication and diversification. Here we demonstrate that KatG1 is...

Many researchers investigating plant-insect interactions maintain their insect colonies on artificial diet and assume that salivary enzymes and elicitors remain representative of natural situations. These salivary elicitors, such as the enzyme glucose oxidase (GOX), play important roles in influencing plant defense responses. In fact, GOX has been implicated in suppressing induced nicotine-prod...

Using transgenic zebrafish (fli1:egfp) that stably express enhanced green fluorescent protein (eGFP) within vascular endothelial cells, we recently developed and optimized a 384-well high-content screening (HCS) assay that enables us to screen and identify chemicals affecting cardiovascular development and function at non-teratogenic concentrations. Within this assay, automated image acquisitio...

We have previously shown that (1) an acute deficiency in blood serum holo-ceruloplasmin (Cp) developed in rats that were fed fodder containing silver ions (Ag-fodder) for one month and (2) the deficiency in holo-Cp was compensated by non-hepatic holo-Cp synthesis in rats that were chronically fed Ag-fodder for 6 months (Ag-rats). The purpose of the present study is to identify the organ(s) that...

The capacity of the refrigerator' is approximately 44 cubic feet. The cabinet is insulated throughout with 4 inches of compressed cork, encased outside with painted plywood and inside with stipple-glazed asbestos sheeting. Internal lighting is provided with automatic operation on opening and closing the doors. Cooling is by means of a Prestcold plate type of evaporator and serviced by a Prestco...

Peroxidases (EC 1.11.1.7) participate in lignin biosynthesis. But peroxidation is not a tool for assaying lignocellulose metabolism because the active cannot yet be separated from the inactive peroxidases. A biochemical tool for assaying plant cell wall responses to agronomic practices is needed in the lignocellulosic feedstock renewable energy industry. Peroxidase of biomass sorghum was purifi...