objective(s): smoking opium/cigarette is a global health concern. the aim of this study was to examine learning and memory of rat male offsprings whose mothers had been exposed to either opium or morphine with nicotine during pregnancy. materials and methods: wistar rats were used for the experiments. in the female rats, opium, morphine and nicotine dependencies were induced by daily injections...

Nicotine addiction leads to in a huge burden on public health and the economy worldwide. Resveratrol (3,5,4’-tetrahydroxystilbene) is most well-known polyphenolic stilbenoid. was shown exhibit positive effects numerous mechanisms that are important for drug substance addiction. Thus, this study aimed examine effect of resveratrol nicotine Intraperitoneal (i.p.) treatment with (0.5 mg/kg) signif...

Background: Melatonin as the major hormone produced by the pineal gland has a significant role in mammalian reproduction. In this study the efficacy of melatonin coadministration with nicotine on mouse follicogenesis was investigated. Materials and Methods: A total of 32 Female adult NMRI mice were divided into four groups. The control group (n=8) received vehicle, group 2 (n=8) received nicoti...

  In this study, we investigated the effect of nicotinic receptor agonists and antagonists on the analgesic response to morphine in the formalin test. In experiments conducted in mice, nicotine produced an early dose-dependent analgesic effect. At a dose of 0.5 mg/kg, mecamylamine, a nicotinic receptor inhibitor, suppressed the analgesic effect induced by 0.1 mg/kg nicotine in both stages of th...

Background: Smoking is a human behavior that has very bad impact on health. Mortality and morbidity due to smoking cannot be under­estimated. Non-communicable diseases become high among smokers, such as diabetes, reduced fertility, coronary heart disease, countless health complications. This study aims analyze the effect of use nicotine gum success cessation based number previous similar studie...

Background: Smoking is one of the most common causes of mortality in the world. Emotional intelligence is the adapting ability to respond to the environment and people appropriately. It plays an important role in various aspects of life such as facing stressful situations and consequently, smoking. This study aimed to investigate the relationship between nicotine dependency and emotional intell...

Background: Nicotine is a substance that can induce oxidative stress in the testes. And thus may reduce fertility in men. Antioxidant supplements such as curcumin can reduce oxidative stress and thus may increase fertility in men. Since the most active component responsible for the yellow color of turmeric and curcumin has anti-inflammatory and antioxidant properties. Therefore this study inves...