INTRODUCTION Patients with idiopathic normal pressure hydrocephalus often show neuropsychiatric symptoms besides the triad of 'classic' symptoms. Memantine has been reported to have positive effects on the neuropsychiatric symptoms of patients with Alzheimer's disease and patients with dementia with Lewy bodies. We administered memantine to a Japanese patient with probable idiopathic normal pre...

OBJECTIVE Neuropsychiatric symptoms are common in Huntington's disease and have been considered its presenting manifestation. Research characterising these symptoms in Huntington's disease is variable, however, encumbered by limitations within and across studies. Gaining a better understanding of neuropsychiatric symptoms is essential, as these symptoms have implications for disease management,...

We report a case of 51 years old woman who suffered from mixed connective tissue disorder (MCTD), complicated by neuropsychiatric manifestation at her initial course of illness. This convoluted her case management, unless the diagnosed was confirmed by skin biopsy. She improved significantly and rapidly on steroid pulse. Neuropsychiatric characteristics are not common presentation in MCTD. Ther...

SEE CORRESPONDING ARTICLE ON PAGE 1127 Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral TraitsBiological PsychiatryVol. 89Issue 12PreviewThe origin of sex differences in prevalence presentation neuropsychiatric behavioral traits is largely unknown. Given established genetic contributions correlations, we tested for a sex-differentiated architecture within betw...

We conducted a case control study to study the association between neuropsychiatric morbidity and group A streptococcal infections in children. Twenty two cases of neuropsychiatric morbidity were compared with 64 controls. Fourteen (63.6%) of the 22 cases were positive for ASO and/or ADNB while 21 of the 64 controls (32.8%) were positive for either or both antibodies (OR = 3.428; CI: 1.15-10.18...