BACKGROUND Isokinetic dynamometry is becoming increasingly important for the assessment of muscle function in individuals with intermittent claudication. However, there is still little information available about the cardiovascular responses of these patients during this type of assessment. OBJECTIVE To assess and compare the cardiovascular responses recorded during the assessment of muscle s...

There are no studies comparing myocardial metabolism between endurance- and resistance-trained athletes. We used 2-deoxy-2-[18F]fluoro-d-glucose and positron emission tomography combined with the euglycemic hyperinsulinemic clamp technique to compare the ability of insulin to stimulate myocardial, skeletal muscle, and whole body glucose uptake between weight lifters ( n = 8), endurance athletes...

Aminimumweekly frequency of concurrent training (1 session per week of strength training and 1 session per week of cycle endurance training) may be an efficient stimulus in elderly in early phases of training; For concurrent-training protocols in which both strength and endurance training are performed on the same day, the strength gains may be optimized with strength training before endurance ...

Background Consumption of tart cherry juice has been reported to increase endurance aerobic performance and attenuate perceptions of muscle soreness by reducing inflammation and oxidative stress that cause secondary muscle damage following endurance exercise. The purpose of this study was to determine if consumption of a powdered form of tart cherries derived from tart cherry skins (CherryPURE ...

This study evaluated the link between swimming endurance and condition of Atlantic cod Gadus morhua that had been fed or starved during the 16 weeks preceding the tests, and assessed whether muscle metabolic capacities explain such links. The condition factor [(somatic mass x fork length(-3))x100] of starved cod was 0.54+/-0.1 whereas that of fed cod was 0.81+/-0.1. In white and red muscle, we ...

Patients with multiple sclerosis (MS) show a poor exercise tolerance. A reduction in respiratory muscle strength has also been reported. The purpose of this study was to evaluate whether reduction in exercise tolerance was related to respiratory muscle dysfunction. Twenty four multiple sclerosis patients (mean +/- SD age: 48 +/- 9 yrs, duration of illness 12.2 +/- 6 yrs, severity of illness as ...

The age-related impairment in muscle function results in a drastic decline in motor coordination and mobility in elderly individuals. Regular physical activity is the only efficient intervention to prevent and treat this age-associated degeneration. However, the mechanisms that underlie the therapeutic effect of exercise in this context remain unclear. We assessed whether endurance exercise tra...

Understanding and managing fatigue is a significant challenge in clinic and society. In attempting to explore how the body responds to and regulates fatigue, we found in rodent fatigue models that orosomucoid 1 (ORM1) was significantly increased in multiple tissues, including blood and muscle. Interestingly, administration of exogenous ORM1 increased muscle glycogen and enhanced muscle enduranc...

For more than one and a half century, the effect of locomotory activity on skeletal muscle structure and function has been studied. It is clear that these changes depend on the mode of activity. Resistance and endurance exercise training differ in their intensity and duration as well as effects on metabolic pathways, structures of skeletal muscle, protein synthesis and degradation rate, neuromu...