multivariate process capability indices (mpci) show how well a manufacturing process can meet specifica-tion limits when quality characteristics enclose a relative correlation. process capability is an important and commonly used metric for assessing and improving the quality of a production process. when quality charac-teristics of a product are correlated then an attractive comes close to mpc...

naphthol isomers were simultaneously and spectrophotometrically determined in wastewater, using a model based on net analyte signal (nas). the calibration method used is a variation of the original hybrid linear analysis method as proposed by goicoechea and olivieri (hla/go). owing to spectral interferences, the simultaneous determination of mixtures of naphthol isomers, using a spectrophotomet...

A newly developed multivariate method involving net analyte preprocessing (NAP) was tested using central composite calibration designs of progressively decreasing size regarding the multivariate simultaneous spectrophotometric determination of three active components (phenylephrine, diphenhydramine and naphazoline) and one excipient (methylparaben) in nasal solutions. Its performance was evalua...

a new fourier transform-infra red (ft-ir) spectrometric method was developed for assaying hydrochlorothiazide (hct) and enalapril maleate (enm) in binary solid pharmaceutical formulations. multivariate partial least squares (pls) method was used for calibration of derivative spectral data. acetonitrile was used as solvent due to its spectral transparency and adequate solubility of analytes in i...