نتایج جستجو برای: metagenomics
تعداد نتایج: 5830 فیلتر نتایج به سال:
Metagenomics is an emerging field in which the power of genome analysis is applied to entire communities of microbes. It is focused on the understanding of the mixture of genes (genomes) in a community as whole. The gene prediction task is a well-known problem in genomics, and it remains an interesting computational challenge in metagenomics too. A large variety of classifiers has been develope...
This report summarizes the events of the 1(st) International Functional Metagenomics Workshop. The workshop was held on May 7 and 8, 2012, in St. Jacobs, Ontario, Canada and was focused on building an international functional metagenomics community, exploring strategic research areas, and identifying opportunities for future collaboration and funding. The workshop was initiated by researchers a...
The pace of research and the development of new areas of focus in biology are increasing at breathtaking speed. Unfortunately, exciting new areas of science typically do not appear in science classrooms and textbooks until many years after their inception. This pattern leaves undergraduate, and especially high school, biology education lagging behind scientific advances. The result is that too ...
Metagenomics is the study of microbial communities on the genome level by direct sequencing of environmental and clinical samples. Recently developed DNA sequencing technologies have made metagenomics widely applicable and the field is growing rapidly. The statistical analysis is however challenging due to the high variability present in the data which stems from the underlying biological diver...
BACKGROUND Bacterial bloodstream infection (bBSI) is one of the leading causes of death in critically ill patients and accurate diagnosis is therefore crucial. We here report a 16S metagenomics approach for diagnosing and understanding bBSI. METHODOLOGY/PRINCIPAL FINDINGS The proof-of-concept was delivered in 75 children (median age 15 months) with severe febrile illness in Burkina Faso. Stan...
Single-cell genomics has unveiled the metabolic potential of dominant microbes inhabiting different environments, including the human body. The lack of genomic information for predominant microbes of the human body, such as bacteriophages, hinders our ability to answer fundamental questions about our viral communities. Here, we applied single-virus genomics (SVGs) to natural human salivary samp...
The use of metagenomics for virus discovery in clinical samples has opened new opportunities for understanding the aetiology of unexplained illness. This study explores the potential of this sequence-independent approach in a public-health setting, by systematic analysis of samples cultured from patients with unexplained illness through a combination of PCR-based assays and viral metagenomics. ...
Metagenomics is a relatively new but fast growing field within environmental biology directed at obtaining knowledge on genomes of environmental microbes as well as of entire microbial communities. With the sequencing technologies improving steadily, generating large amounts of sequence is becoming routine. However, it remains difficult to connect specific microbial phyla to specific functions ...
Metagenomics (also referred to as environmental and community genomics) is the genomic analysis of microorganisms by direct extraction and cloning of DNA from an assemblage of microorganisms. The development of metagenomics stemmed from the ineluctable evidence that as-yet-uncultured microorganisms represent the vast majority of organisms in most environments on earth. This evidence was derived...
The world of microorganisms comprises a vast diversity of live organisms, each with its individual set of genes, cellular components and metabolic reactions that interact within the cell and communicate with the environment in many different ways. There is a strong imperative to gain a broader view of the wired and interconnected cellular and environmental processes as a whole via the systems m...
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