This essay examines how some psychologically adroit individuals use creativity as a manic defence against the affects that they cannot bear to experience directly. Conceived within the perspectives of Jungian psychoanalysis, manic creativity is shown to effect a defence against the subjective distress of personal complexes by means of an identification with the archetypal cores of the complexes...

The separation of manic depressive illness from schizophrenia was an important diagnostic task undertaken early on by Kraepelin (1896, 1919) who saw schizophrenia (“dementia praecox”) as a psychotic illness and a thought disorder, characterised by a steady downhill in cognition leading to chronic dementia, whereas manic depressive illness was seen as an episodic affective disorder with intermit...

case presentation an elderly woman in a manic phase of bipolar disorder without a previous history of psychiatric disorders was concomitant with problematic sexual over stimulation in the context of hyper sexuality. she had traumatized her genitals and underwent surgery for their repair. following her admission and psychopharmacologic therapy, she recovered. introduction late onset bipolar diso...

Recurrent manic-like episodes can be induced by hyponatremia possibly due to empty sella syndrome. In the present case, the patient was proven to have syndrome of inappropriate antidiuretic hormone (SIADH) secretion with manic symptoms that resolved after the normalization of the plasma sodium level.To our knowledge, this is the first case of hyponatremia-induced manic symptoms in a patient wit...

Genetic and pharmacological studies have suggested that brain-derived neurotrophic factor (BDNF) may be associated with the pathophysiology of bipolar disorder (BD). The present study investigated serum BDNF levels in manic, depressed, euthymic BD patients and in matched healthy controls, using an enzyme-linked immunosorbent assay (sandwich-ELISA). Serum BDNF levels were decreased in manic (p=0...

Background: Disturbances in thought, speech, and linguistic processing are frequently observed in bipolar manic patients, but the underlying neurophysiological mechanisms are not well understood. P600 is a distinct, positive event-related potential component elicited by syntactic violations. Using the P600 ERP, we examined neural processing of syntactic language comprehension in patients with b...