Over the last years, digital preservation has become a particularly active research area. While several initiatives are dealing with the preservation of standard document formats, the challenges of preserving multimedia objects and pieces of electronic art are still to be tackled. This paper presents the findings of a pilot project for preserving born-digital interactive multimedia art. We desc...

BACKGROUND Although WHO recommends starting antiretroviral treatment at a CD4 count of 350 cells/[µ]L, many Ugandan districts still struggle with large proportions of clients initiating ART very late at CD4<50 cells/[µ]L. This study seeks to establish crucial risk factors for very late ART initiation in eastern Uganda. METHODS All adult HIV-infected clients on ART in Iganga who enrolled betwe...

BACKGROUND Estimation of the number of people in need of antiretroviral therapy (ART) in resource-limited settings requires information on the time from seroconversion to ART eligibility and from ART eligibility to death. OBJECTIVES To estimate duration from seroconversion to different ART eligibility criteria and from ART eligibility to death in HIV-infected adults in low-income and middle-i...

FOREWORD SEVERAL YEARS AGO, Karl Narr asked me to write an article summarizing the recently discovered data of Southeast Asian prehistory for publication in German in Saeculum. In the fall of 1977, I finally did this in the context of an examination of a number of Heine-Ge1dern's hypotheses on Southeast Asian prehistory. I titled the paper "New data on late Southeast Asian prehistory and their ...

BACKGROUND South Africa has a significant burden of tuberculosis (TB). Anti-TB drug-induced liver injury (TB DILI) is one of the most serious adverse events that can arise from TB treatment (TBT). There are limited data on TB DILI among HIV-infected patients and those on antiretroviral therapy (ART). OBJECTIVE To describe characteristics of HIV-infected patients presenting with TB DILI and th...

BACKGROUND We aimed to determine whether antiretroviral therapy (ART) initiation with efavirenz (EFV) is associated with decreases in 25-hydroxyvitamin D (25[OH]D) compared with non-EFV regimens. METHODS 25(OH)D was measured from stored plasma samples in 87 ART-naive HIV-positive patients prior to ART initiation with EFV-containing (n=51) or non-EFV-containing (89% with protease inhibitors; n...