Immune chronic active hepatitis is a disease notorious for its unpredictability. In a patient with chronic hepatitis who has already suffered relapses a search for a second cause of jaundice is not usually necessary. This report emphasises the essential role of liver biopsy.

Signaling through the cyclic adenosine monophosphate-dependent protein kinase [protein kinase A (PKA)] is an important and widely studied area of signal transduction research. This signaling pathway is commonly investigated through the use of the pharmacological PKA inhibitors H89 and KT 5720. Both of these compounds are thought to block PKA actions through competitive inhibition of the adenosi...

A 54-year-old Spanish woman sought medical advice at the outpatient clinic of our institution for diarrhoea and abdominal pain that began on her return from Cambodia and Laos ten days earlier. On examination, she had neither fever nor skin lesions. Laboratory tests showed haemoglobin, hepatic enzymes and a leucocyte count within normal range. No eosinophilia was detected. The patient was diagno...