1. L-Valine, L-leucine and L-isoleucine containing "N were prepared, purified, and fed to marasmic and recovered infants. The excretion of total "N and ["Nlurea in the urine was followed for 72 h. 2. "N excreted from isoleucine was about 90 %, from leucine 70 %, and from valine 50 % in the recovered child. 3. "N excreted was lower for leucine and isoleucine in marasmus than in recovery. The cli...

The isotope studies of Strassman et al. (3, 4) first implicated cu-acetolactate and cu-aceto-cY-hydroxybutyrate as biosynthetic precursors of valine and isoleucine, respectively. The observed accumulation of acetolactate by Escherichia coli (5, 6) and of the decarboxylation products of acetolactate and acetohydroxybutyrate by Neurospora crassa (7) when mutants of these organisms are grown with ...

The objective of this study was to determine the Ile requirement in early (d 39 to 61) and late (d 89 to 109) pregnancy using the indicator AA oxidation method. The same 7 Large White × Landrace sows in their fourth parity were used in early and late pregnancy. Each sow received 6 diets based on corn, corn starch, and sugar in both early and late pregnancy at constant feed allowances (2.5 kg/d)...

The title compound, {2-[(2-carbamoyleth-yl)amino]-3-methyl-penta-noic acid}, C(9)H(18)N(2)O(3), is of inter-est with respect to its biological activity. It was formed during an addition reaction between acryl-amide and the amino acid isoleucine. The crystal structure is a three-dimensional network built up by inter-molecular N-H⋯O and O-H⋯N hydrogen bonds.

Introduction and Aim: Diabetes mellitus is a complex disease that major global health problem. It defined as chronic metabolic characterized by high blood glucose levels. risk has been linked to genetic variations within mitochondrial DNA. The current study sought identify compare variation (mutations) in ATPase genes diabetic patients healthy individuals. Materials Methods: This included 100 i...

In view of the rather high percentage of nitrogen in molds it is surprising to note the scarcity of reports concerning their amino acid content. Few amino acids have been reported, and still fewer have been isolated and characterized by analysis and by the formation and examination of suitable derivatives. Leutine, both free (1) and combined (2), has been reported in Aspergillus aiger, but no r...

In Escherichia coli the sulfur-containing amino acid homocysteine (Hcy) is the last intermediate on the methionine biosynthetic pathway. Supplementation of a glucose-based minimal medium with Hcy at concentrations greater than 0.2 mM causes the growth of E. coli Frag1 to be inhibited. Supplementation of Hcy-treated cultures with combinations of branched-chain amino acids containing isoleucine o...

A three-dimensional structure comparison between the dimeric regulatory serine-binding domain of Escherichia coli D-3-phosphoglycerate dehydrogenase [Schuller, D. J., Grant, G. A., and Banaszak, L. J. (1995) Nat. Struct. Biol. 2, 69-76] and the regulatory domain of E. coli threonine deaminase [Gallagher, D. T., Gilliland, G. L., Xiao, G., Zondlo, J., Fisher, K. E., Chinchilla, D. , and Eisenste...