نتایج جستجو برای: intravenous iron
تعداد نتایج: 218815 فیلتر نتایج به سال:
D uring the past decade, the integration of recombinant human erythropoietin (EPO) and maintenance intravenous iron therapy into standard anemia management protocols has significantly altered the treatment of anemia in patients who are on hemodialysis (HD). Hemoglobin levels have increased inexorably and now average almost 12 g/dl (1). The National Kidney Foundation Kidney Disease Outcomes Qual...
Iron deficiency anemia is the most common form of anemia worldwide, caused by poor iron intake, chronic blood loss, or impaired absorption. Patients with inflammatory bowel disease (IBD) are increasingly likely to have iron deficiency anemia, with an estimated prevalence of 36%-76%. Detection of iron deficiency is problematic as outward signs and symptoms are not always present. Iron deficiency...
BACKGROUND Studies on benefits of intravenous iron therapy among hemodialysis patients with functional iron deficiency anemia have shown conflicting results. We conducted a meta-analysis to assess the efficacy and safety of intravenous iron in this subset of patients. METHODS We searched MEDLINE (through December 2012), the Cochrane Central Register of Controlled Trials and ClinicalTrials.gov...
BACKGROUND Iron deficiency is the most common single cause of anemia worldwide. Treatment consists of improved nutrition along with oral, intramuscular or intravenous iron administration. OBJECTIVES To describe the efficacy and adverse effects of intravenous iron sucrose therapy in a group of children with iron deficiency anemia who did not respond to oral iron therapy. METHODS We conducted...
Iron is an element necessary for cells due to its capacity of transporting oxygen and electrons. One of the important co-morbidities in heart failure is iron deficiency. Iron has relevant biological functions, for example, the formation of haemoglobin, myoglobin and numerous enzymatic groups. The prevalence of iron deficiency increases with the severity of heart failure. For a long time, the in...
Iron deficiency anaemia (IDA) still becomes major health problem all over the world and pregnant women at particular risk. IDA is associated with negative outcomes for both mother and infant. Therefore, many laboratory assessments can be used as estimation of iron status during pregnancy, with haemoglobin (Hb) and serum ferritin (SF) as the most widely used tools. However, the uses of these two...
Background: For iron therapy in hemodialysis patients, intravenous rather than oral administration is recommended. Methods: For hemodialysis patients with serum ferritin levels less than 200 ng/ml (less than 100 ng/ml: 67 patients, between 100 and 199 ng/ml: 20 patients) with no iron therapy for more than 3 months, iron was administered intravenously (40 mg of ferric oxide saccharate for ten ti...
BACKGROUND Preclinical studies demonstrate renal proximal tubular injury after administration of some intravenous iron preparations but clinical data on renal effects of intravenous iron are sparse. METHODS FIND-CKD was a 56-week, randomized, open-label, multicenter study in which patients with non-dialysis dependent chronic kidney disease (ND-CKD), anemia and iron deficiency without erythrop...
Intravenous iron preparations are typically classified as non-dextran-based or dextran/dextran-based complexes. The carbohydrate shell for each of these preparations is unique and is key in determining the various physicochemical properties, the metabolic pathway, and the immunogenicity of the iron-carbohydrate complex. As intravenous dextran can cause severe, antibody-mediated dextran-induced ...
Sterile inflammation induced by repeated subcutaneous injections of turpentine in non-anemic, non-iron-deficient dogs, leads to a fall in plasma iron concentration, the development of a moderate anemia, and a marked delay in the uptake by the red blood cells of intravenous radioiron. Similar periods of inflammation in anemic, iron-deficient dogs on a diet low in iron cause no increase in the de...
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