Genetic diversity in perennial Salvia judaica Boiss (Judean sage) and palaestina Benth (Palestinian species using touch-up directed amplification of minisatellite region DNA (TU-DAMD) has been performed two separated sets; the first set (set A) initial annealing temperature was increased from 50 °C to 55 °C, whereas, second one B), it 60 by 0.5 °C/cycle during 10 PCR cycles. Fifteen DAMD primer...

The literature review presents the characteristics of human leukocyte antigen (HLA)-B27 as a factor contributing to development psoriatic arthritis. HLA-B27 is class I surface encoded by major histocompatibility complex (MHC) B locus located on chromosome 6. main function present antigenic peptides CD8+ T-cells. most important genetic biomarker for arthritis, it provides phenotypic differentiat...

the genetic polymorphism of insulin-like growth factor binding protein ( igfbp-3 ) and its association with the growth traits namely condition factor, body weight, and total length were investigated in common carp cyprinus carpio using pcr- single strand conformation polymorphism (sscp) technique. caudal fin clips from 120 c. carpio , aging 5 months, were used in this study and a 330 bp dna fra...

This study describes the genetic relationships among 34 varieties of Lallemantia iberica using inter-retrotransposon amplified polymorphism (IRAP) and retrotransposon-microsatellite amplified polymorphism (REMAP). Samples were collected from Agriculture Research Center of Urmia city (northwest Iran). Ten IRAP and REMAP primers generated 76 scorable electrophoretic bands with 78.94% pol...

Background and Aims: Asthma is a complicated chronic inflammatory disease associated with pulmonary inflammation, severe immune responses of the respiratory tract, and change or destruction in the respiratory tract structure. Several factors, especially genetic and environmental factors, contribute to the pathogenesis of asthma. Interlukin (IL)-13 is considered the most important inflammatory m...

Background: Major histocompatibility complex (MHC) is one of the best characterized genetic regions controlling immune responses against vaccines. Identifying the association between MHC haplotypes and improved immune responses would be useful in genetic breeding strategies in animals. OBJECTIVES: MHC class II B genetic diversity and its association with humoral immune responses against Newcast...

BACKGROUND Genetic variants of proteins involved in lipid metabolism may play an important role in determining the susceptibility for complications associated with type II diabetes mellitus (T2DM). Goal of the present study was to determine the association of cholesteryl ester transfer protein TaqI B, D442G, and APOE Hha I polymorphisms with T2DM and its complications. METHODS Study subjects ...

High blood pressure (BP) and elevated homocysteine are reported as independent risk factors for CVD and stroke in particular. The main genetic determinant of homocysteine concentrations is homozygosity (TT genotype) for the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene, typically found in approximately 10% of Western populations. The B-vitamins folate, vitamin B12 a...

Background: 6-Mercaptopurine (6-MP), a widely used anti-metabolite for the maintenance phase of childhood acute lymphoblastic leukemia (ALL), has been observed to cause myelotoxicity due genetic polymorphism thiopurine methyl transferase (TPMT), one drug-metabolizing enzymes. This study aimed determine frequency S-methyl (TPMT) polymorphic variants in group Pakistani children with (ALL) using 6...

BACKGROUND Combination therapy with budesonide and formoterol reduces exacerbations of asthma, which are closely associated with human rhinovirus (RV) infections in both children and adults. These data suggest that budesonide and formoterol inhibit virus-induced inflammatory responses of airway epithelial cells. METHODS To test this hypothesis, bronchial epithelial (BE) cells were obtained fr...