Introduction. Clear understanding of duration antibody based protective immunity following natural infection with SARSCoV- 2 will give idea about the efficacy proposed prophylactic vaccines against SARS-CoV-2, establishment herd and use convalescent plasma. Aim. This study clarified kinetics magnitude initial response SARS-CoV-2 in a cohort symptomatic COVID-19 patients from Ibadan, Nigeria. Ma...

Introduction Myelin-oligodendrocyte glycoprotein antibody (MOG)–associated disorder (MOGAD) is a recently identified immune-mediated inflammatory of the central nervous system (CNS). The significance oligoclonal bands (OCBs) not fully elucidated. This study investigated clinical differences between patients with MOGAD who tested positive or negative for OCBs. Methods was conducted on 23 MOG-IgG...

Background and Objectives The cytotoxin-associated gene (cag) pathogenicity island is reported to be a major virulence factor of Helicobacter pylori infection. It is previously reported that the cagA-positive strains are more virulent, so it can be postulated that the cagA-positive gastritis will be more severe and the serum immunoglobulin G (IgG) and A(IgA) anti-CagA antibody titer will be hig...

The mechanism of protection of type-specific antipneumococcal antibody and complement in bacteremia was investigated with purified rabbit antibody and a guinea pig model of pneumococcal bacteremia. IgG and IgM were isolated from the sera of rabbits immunized with type 7 pneumococci (Pn), and their binding to Pn was quantitated. The number of antibody-binding sites on the pnuemococcal capsule wa...

Antigen-specific IgG antibodies, passively administered to mice or humans together with large particulate antigens like erythrocytes, can completely suppress the antibody response against the antigen. This is used clinically in Rhesus prophylaxis, where administration of IgG anti-RhD prevents RhD-negative women from becoming immunized against RhD-positive fetal erythrocytes aquired transplacent...

BACKGROUND Pemphigus is an autoimmune bullous disease and it is unclear what triggers and deteriorates it. The current study aimed to evaluate whether increasing the IgG antibody titer represents a good indicator of the pemphigus recurrence. OBJECTIVES The current study aimed to evaluate whether increasing IgG titer is an indicator of the expected recurrence. PATIENTS AND METHODS The curren...

OBJECTIVES To identify valuable antiganglioside antibodies that support the diagnosis of Guillain-Barré syndrome (GBS) and its variants in patients showing bulbar palsy as an initial symptom. METHODS Medical records of 602 patients with GBS or its variants were reviewed. Fifteen patients had bulbar palsy as an initial symptom. Serum antibodies against GM1, GM1b, GD1a, GalNAc-GD1a, GT1a, and G...

Toxoplasma gondii infection causes high rate of gestational and congenital across the globe is considered a both public health problem neglected disease. The study was carried out to determine prevalence anti-Toxoplasma antibodies associated risk factors among pregnant women attending antenatal care in some Primary Health Centres Jos, Plateau State, Nigeria. In this cross-sectional within 5 mon...

Rabbit antibodies for Candida albicans, reacting in agglutination and fluorescent-antibody reactions, were present in both IgM and IgG protein fractions. The two types of immune globulins were separated from ammonium sulfate-precipitated gamma-globulin either by filtration through a column of Sephadex G-200 or by diethylaminoethyl column chromatography performed by stepwise elution with various...

Raised serum IgG and IgM antibody levels to native type II collagen were found in patients with rheumatoid arthritis and in patients with juvenile chronic arthritis. There was a good correlation between the serum IgG and the IgM antibody levels in rheumatoid arthritis and a weaker correlation in juvenile chronic arthritis. Raised serum IgM antibody levels to native type II collagen were found i...