نتایج جستجو برای: hydroxybenzoic acids
تعداد نتایج: 265698 فیلتر نتایج به سال:
The O-tosylsalicylamide S3I-201 (10) was used as a starting point for design and synthesis of novel STAT-3 dimerization inhibitors with improved drug-like qualities. The phosphonic acid 12d and salicylic acids 13f, 13g with a shorter amide linker lacking the O-tosyl group had improved STAT-3 inhibitory activity. The equivalent potencies observed by the replacement of phosphonic acid moiety of 1...
BACKGROUND AND AIMS Epidemiologic and biological evidence supports an inverse association between polyphenol consumption and the risk of cardiovascular disease (CVD). However, no previous studies have prospectively evaluated the relationship between polyphenol intake and the incidence of CVD in such a comprehensive way. The aim was to evaluate the association between intakes of total polyphenol...
The phenomenon that wild grasses did not grow beneath the tree of Quercus mongolica Fisch var. grosseserrata Rehd. Wils. while they grew vigorously beneath other species of trees around Q. mongolica was observed in many places in the Hokkaido district. The allelochemicals in the soil beneath Q. mongolica were studied. This soil inhibited the growth of lettuce (Lactuca scariola L. var. sativa Bi...
Background Bamboo shoot has been used as a treatment for epilepsy in traditional Chinese medicine for generations to treat neuronal disorders such as convulsive, dizziness and headaches. 4-hydroxybenzoic acid (4-hba) is a non-flavonoid phenol found abundantly in Dendrocalamus asper shoots (bamboo), fruits (strawberries and apples) and flowers. Kv1.4 is a rapidly inactivating Shaker-related memb...
In this study, we investigate the potential of Moricandia arvensis methanol leaf extract (MeOHL) on calpain activity, melanin biosynthesis and DNA mutagenicity. Cytotoxic effect and measurement of reactive oxygen species (ROS) induced by lucigenin in colorectal cells (BE) were also determined. In addition the chemical analysis of the extract was also studied and the chemical profile illustrates...
Wildfires and their emissions have significant impacts on ecosystems, climate, atmospheric chemistry, and carbon cycling. Well-dated proxy records are needed to study the long-term climatic controls on biomass burning and the associated climate feedbacks. There is a particular lack of information about long-term biomass burning variations in Siberia, the largest forested area in the Northern He...
A free and liberated by acid and alkaline hydrolysis phenolic acids from the hips of fourteen species of wildly growing roses were identifed and determined using SPE RP HPLC method. Eleven major phenolic acids (gallic, protocatechuic, gentisic, p-hydroxybenzoic, vanillic, caffeic, syringic, p-coumaric, ferulic. p-hydroxyphenylacetic, salicylic) were quantitatively investigated. The amount of in...
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