BACKGROUND Human neutrophil antigens (HNAs) are involved in autoimmune and alloimmune neutropenia and transfusion-related acute lung injury. The HNA-1 system is important in immunogenetics, and allele frequencies have been described in different populations. This study investigated the frequency of FCGR3B alleles encoding HNA-1a, HNA-1b, and HNA-1c among Thai blood donors and compared these fre...

Oxidation of low-density lipoproteins (LDL) generates high concentrations of unsaturated aldehydes, such as 4-hydroxy trans-2-nonenal (HNE). These aldehydes are mitogenic to vascular smooth muscle cells and sustain a vascular inflammation. Nevertheless, the processes that mediate and regulate the vascular metabolism of these aldehydes have not been examined. In this communication, we report the...

Microalbuminuria (MA) is an important early sign of diabetic nephropathy. Hyperfiltration and impaired filtration in relation to albuminuria has been well investigated in diabetic subjects. This study tested the hypothesis that an increased urinary albumin excretion (UAE) is associated with renal functional abnormalities also in nondiabetic subjects. The relation between UAE and creatinine clea...

INTRODUCTION People living with and beyond cancer are vulnerable to a number of physical, functional and psychological issues. Undertaking a holistic needs assessment (HNA) is one way to support a structured discussion of patients' needs within a clinical consultation. However, there is little evidence on how HNA impacts on the dynamics of the clinical consultation. This study aims to establish...

Bacterioplankton was studied in a large area of Southwest Atlantic Ocean between 13 and 25oS and 28 and 42oW. Samples were collected in 108 stations at 20 m depth. Bacteria were enumerated by flow cytometry after nucleic acid staining with syto13 and two subgroups were differentiated: low nucleic acid content (LNA) and high nucleic acid content (HNA) bacteria. Total bacterial numbers varied fro...

Los cuidados paliativos son una forma de enfoque que busca la humanización y comodidad del paciente en situación enfermedad crónica, independientemente subyacente. En esta perspectiva, búsqueda participación conjunta equipo atención multidisciplinar, el su familia es principal objetivo. La nutrición pediátrico debe verse como algo puede ofrecer beneficios, pero también riesgos, indicación ser o...

Hyperkeratosis of the nipple and areola (HNA) is an uncommon condition characterized by verrucose thickening and café-au-lait pigmentation of the nipple and areola.1 It was first described by Tauber in 1923 and approximately 70 cases have been published to date in the medical literature. Several therapeutic approaches have been used to treat this condition, although no gold standard has yet bee...

An algorithm for non-intrusively coupling a commercial finite element software with a research code implementing a hierarchical enrichment of finite element spaces is presented. Examples of hierarchical methods supported by the algorithm are the Generalized or eXtended FEM (GFEM), the scale-bridging GFEM with numerically defined enrichment functions (GFEMgl), and the p-version of the FEM. The p...

1. Morishita K, Wakamoto S, Miyazaki T, Sato S, Fujihara M, Kaneko S, Yasuda H, Yamamoto S, Azuma H, Kato T, Ikeda H. Life-threatening adverse reaction followed by thrombocytopenia after passive transfusion of fresh frozen plasma containing anti-CD36 (Nak) isoantibody. Transfusion 2005; 45:803-6. 2. Nakajima F, Nishimura M, Hashimoto S, Okazaki H, Tadokoro K. Role of anti-Naka antibody, monocyt...