Ten diffuse histiocytic lymphoma (DHL) cell lines were extensively characterized with monoclonal antibodies and histochemical techniques. The original biopsy specimens. representing nine of ten cases from which the cell lines were derived. were reviewed utilizing the International Working Formulation. Eight of ten cell lines reacted with antiimmunoglobulin reagents and/or a subset of B-Iymphocy...

Thirty previously treated adults with lymphoma received AMSA as single agent therapy. All patients had previously received adriamycin-containing chemotherapy regimens and either failed to respond initially or responded but subsequently relapsed. The dose used was 40 mg/sq m.i.v. daily x3. For patients with compromised marrow reserve or elevated bilirubin, a 25% reduction was used. Ten of 30 pat...

Malignant Lymphoma is uncommon in female genital tract. A rare presentation of Malignant Lymphoma of the vagina has been reported here. A 61 years old woman presented with postmenopausal bleeding of 10 days duration. On examination per vaginum, the patient had firm nodular infiltrative growth involving entire posterior vaginal wall and full thickness of recto-vaginal septum. Bleeding ulcer was ...

We have studied the antileukemic effects of cyclosporin-A (CyA) on the cells of a number of human hematopoietic biopsies and established cell lines in vitro. Cya killed the tumor cells but not the nonmalignant control cells from three of four patients with T-lymphocytic leukemia/lymphoma at concentrations comparable to those recommended in clinical long-term immunosuppressive therapy. The leuke...

Case history: Malignant lymphoma is a neoplastic proliferative process of the lymphopoietic portion of the reticuloendothelial system that involves cells of either the lymphocytic or histiocytic series in varying degrees of differentiation and occurs in an essentially homogenous population of a single cell type. The character of histologic involvement is either diffuse (uniform) or nodular and ...

To cite: Mannu GS, Ahmed F, Cunnick G, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-203100 DESCRIPTION A healthy 19-year-old woman presented to her general practitioner with a 2-month history of a right axillary lump. There were no breast lesions and a general clinical examination was unremarkable. The lump was thought to be an enlarged lymph node ...