نتایج جستجو برای: histiocytes
تعداد نتایج: 1490 فیلتر نتایج به سال:
A 47-year-old man presented with hemophagocytic syndrome (HPS) without any obvious underlying diseases. On computed tomography, his liver was occupied by multiple ill-defined low intensity lesions. Liver biopsy revealed diffuse infiltration of numerous histiocytes without cytologic atypism and prominent fibrotic changes. These histiocytes showed S100(+), CD68(+), CD1a(-), and lysozyme(+) and La...
Xanthogranuloma is one of the 2 disorders of non-Langerhan cell histocytoses. It is a benign tumor histologically characterized by foamy histiocytes, numerous Touton giant cells and rare eosinophils. The histology differs from Langerhan cell histocytosis disorders in which convoluted histocytes, numerous eosinophils and rare Touton cells are seen. Grossly, the lesion appears as golden yellow pa...
histiocytic syndromes have been studied and investigated in these recent years for their cell origin, morphology, pathology, histochemical, immuno-phenotype characteristic, and their nomenclature, but the results of all these studies are confusingly, vague and not acceptable for all scientists and pathologists. histiocytes very in the morphology, duty and their immunological behaviour. in diffe...
A 77-year-old man was admitted for evaluation of pancytopenia. His blood examination revealed hemoglobin 9.7 g/dL, platelet count 149 3 10/L, and white blood cell count 3.2 3 10/L with normal differential. Peripheral blood smear showed red blood cells with anisocytosis, microcytes, and teardrop-shaped cells. There was mild leukopenia with relative monocytosis and normal platelets. Bone marrow b...
Some of the problems which we see on the infectious disease consultation service can be quite frustrating. This is one such case. A middle-aged man presented to our medical service with fever and dyspnea. His fulminant downhill course was characterized by anemia, jaundice, hypercalcemia, pulmonary abnormalities, and a lack of responsiveness to conventional antimicrobial therapy. At autopsy, mal...
Extensive immunophenotypic studies in a 2 1/2 month old girl with haemophagocytic lymphohistiocytosis were performed to characterise the proliferating histiocytes of the disease. The cells strongly expressed conventional macrophage antigens, but unexpectedly, there was a dissociated expression of the CD1a antigen (reacting with the monoclonal antibody NA1/34 but not with OKT6) and intracellular...
Chronic granulomatous disease (CGD) results from a congenital bactericidal defect within phagocytic cells including neutrophils (3, 9, 17, 18), and has been characterized by the formation of granulomas in generalized organs and by the appearance of histiocytes containing pigmented lipid materials mainly in the reticulo-endothelial system (1, 2). Although one histochemical and ultrastructural re...
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