نتایج جستجو برای: hb a1c

تعداد نتایج: 20311  

Journal: :Clinical chemistry 1987
A Mosca A Carenini F Zoppi A Carpinelli G Banfi F Ceriotti P Bonini G Pozza

The fructosamine test for assessing control of glucose in blood has been extensively evaluated, but some questions remain regarding its validity. From the analytical and clinical evaluation we present here, we conclude that: the test is sensitive to variations in the composition of the sample protein; the fructosamine reaction is almost completely unaffected by labile fractions; the concentrati...

Journal: :British medical journal 1978
A L Kennedy T R Lappin T D Lavery D R Hadden J A Weaver D A Montgomery

Serum cholesterol and high-density lipoprotein (HDL) cholesterol concentrations were measured in 192 diabetics (94 with juvenile-onset and 98 with maturity-onset diabetes) and 177 non-diabetic controls. Hb A1C, an index of blood sugar control, was also measured in the diabetics. Serum cholesterol concentrations were similar in all the diabetics and controls, but HDL cholesterol concentrations w...

2011
Mami Nakamura Ayako Miyazaki Takayuki Takubo Yoko Matsuzawa Jun Saito Masao Omura Tetsuo Nishikawa

Hemoglobin A1c (HbA1c) is an important parameter for evaluating long-term (6-8 weeks) control of blood glucose levels in patients with diabetes mellitus. We report a Japanese diabetic case who harbored abnormal Hb and demonstrated falsely low HbA1c levels in the regular ion exchange HPLC-based assay. His abnormal β-globin chain had an amino acid replacement that corresponded to glycine to serin...

Tarjoman,, A,

SUMMARY: At present, measurment of glycosylated hemoglobin, especially the stable fraction of hemoglobin (HbA1c) is one of the ways to control diabetes because this measurment can demonstrate total glycemia during last 1.2.3 months. Glycosylated hemoglobin is seen in 3 forms: Ala Alb A1c. Among these hemoglobin Alc is quantitively more than other 2 forms and its difference with other hemoglobi...

2010
April P. Carson Kristi Reynolds Vivian A. Fonseca Paul Muntner

OBJECTIVE To compare A1C and fasting glucose for the diagnosis of diabetes among U.S. adults. RESEARCH DESIGN AND METHODS This study included 6,890 adults (> or =20 years of age) from the 1999-2006 National Health and Nutrition Examination Survey without a self-reported history of diabetes who had fasted > or =9 h. A1C > or =6.5% and fasting glucose > or =126 mg/dl were used, separately, to d...

Journal: :Analytical chemistry 2013
Hong Liu Richard M Crooks

We report a potentiometric method for measuring the hemoglobin A1c (HbA1c, glycated hemoglobin) concentration, hemoglobin (Hb) concentration, and percent HbA1c (%HbA1c) in human blood hemolysate. The %HbA1c is important for diagnosis and management of diabetes mellitus. Alizarin red s (ARS) is used as a redox indicator. Phenylboronic acid (PBA) binds to both ARS and HbA1c via diol-boronic acid ...

Journal: :Clinical chemistry 2014
Randie R Little

Two very interesting articles on hemoglobin A1c (Hb A1c) 2 method performance appear in this issue of Clinical Chemistry. Woodworth et al. (1 ) use Hb A1c as an example of how the risk of reporting inaccurate results can be estimated to guide individualized QC strategies. They assess the risk of reporting unreliable Hb A1c results with 6 different methods in 4 academic medical centers; 5 are la...

2013
Mehmet Agilli Halil Yaman Fevzi Nuri Aydin Erdinc Cakir Tuncer Cayci Yasemin Gulcan Kurt Emin Ozgur Akgul Ibrahim Aydin

In this article, an interference caused by hemoglobin H (Hb H), during the measurement of hemoglobin A1c (HbA1c) with ion exchange high pressure liquid chromatography (HPLC) method, was presented in blood sample of a 20-year-old male patient. HbA1c measurement was performed with Agilent 1200 HPLC system using a commercial Recipe HbA1c ion-exchange column. Hemoglobin electrophoresis was performe...

2008
JM Gamble Scot H Simpson Lauren C Brown Jeffrey A Johnson

BACKGROUND Although evidence-based guidelines for the treatment of type 2 diabetes mellitus provide clear recommendations for initial therapy, evidence on an optimal treatment strategy after secondary failure is unclear. PURPOSE To compare the efficacy of add-on therapy using basal insulin versus an additional oral antidiabetic agent in patients with type 2 diabetes and secondary failure. D...

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