نتایج جستجو برای: guanine cytosine

تعداد نتایج: 18709  

Journal: :Organic & biomolecular chemistry 2011
Hao-Zhe Yang Mei-Ying Pan Da-Wei Jiang Yang He

Novel Janus type nucleoside analogues 1a and 1b were synthesized in seven steps from 2-amino-4,6-dihydroxypyrimidine and 4,6-dihydroxypyrimidine. The base moiety of 1a has one face with a Watson-Crick donor-donor-acceptor (DDA) H-bond array of guanine and the other face with an acceptor-acceptor-donor (AAD) array of cytosine, which might lead to its base pairing with either cytosine or guanine ...

Journal: :Analytical chemistry 2002
Daniel P Glavin Michael Schubert Jeffrey L Bada

A sublimation technique was developed to isolate purines and pyrimidines directly from lambda-deoxyribonucleic acid (lambda-DNA) and Escherichia coli cells. The sublimation of adenine, cytosine, guanine, and thymine from lambda-DNA was tested under reduced pressure (approximately 0.5 Torr) at temperatures of >150 degrees C. With the exception of guanine, approximately 60-75% of each base was su...

Journal: :Wikijournal of science 2023

Non-canonical base pairs are planar hydrogen-bonded of nucleobases, having hydrogen bonding patterns which differ from the observed in Watson-Crick pairs, as classic double-helical DNA. The structures polynucleotide strands both DNA and RNA molecules can be understood terms sugar-phosphate backbones consisting phosphodiester-linked D 2’ deoxyribofuranose (D ribofuranose RNA) sugar moieties, wit...

Journal: :The Journal of Cell Biology 1963
J. -E. Edström J. G. Gall

The base composition of RNA's extracted from chromosomes, nucleoli, nuclear sap, and cytoplasm of Triturus oocytes has been determined by microelectrophoresis. The chromosomal RNA has a content of guanine+cytosine equal to that of DNA, but there is no complementarity in the composition as for DNA. Nuclear sap contains a highly variable RNA with a tendency towards high uracil values. Nucleolar a...

Journal: :The journal of physical chemistry. A 2005
Brina Brauer R Benny Gerber Martin Kabelác Pavel Hobza Joost M Bakker Ali G Abo Riziq Mattanjah S de Vries

The results of harmonic and anharmonic frequency calculations on a guanine-cytosine complex with an enolic structure (a tautomeric form with cytosine in the enol form and with a hydrogen at the 7-position on guanine) are presented and compared to gas-phase IR-UV double resonance spectral data. Harmonic frequencies were obtained at the RI-MP2/cc-pVDZ, RI-MP2/TZVPP, and semiempirical PM3 levels o...

Journal: :Carcinogenesis 2000
V M Arlt M Wiessler H H Schmeiser

The distribution of DNA adducts formed by the two main components, aristolochic acid I (AAI) and aristolochic acid II (AAII), of the carcinogenic plant extract aristolochic acid (AA) was examined in a plasmid containing exon 2 of the mouse c-H-ras gene by a polymerase arrest assay. AAI and AAII were reacted with plasmid DNA by reductive activation and the resulting DNA adducts were identified a...

Journal: :Menopause 2016
Heather S Hipp Krista H Charen Jessica B Spencer Emily G Allen Stephanie L Sherman

OBJECTIVE Approximately 20% of women with a premutation in the FMR1 gene experience primary ovarian insufficiency (POI). We explored diagnostic patterns, frequency of appropriate hormone replacement, obstetric outcomes, fertility treatment, reproductive decisions, and counseling of women with fragile X-associated POI (FXPOI). METHODS Semistructured interviews with 79 women with FXPOI were con...

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