BACKGROUND AND OBJECTIVES The current pharmacological management of diabetic gastroparesis remains difficult. Acupuncture has been widely used for gastrointestinal symptoms. The aim of this study was to investigate the effects of electroacupuncture (EA) on solid gastric emptying time, serum gastrin, motilin, pancreatic polypeptide (PP), fasting and postprandial blood glucose, and symptoms in pa...

Gastroparesis is a motility disorder of the stomach causing delay in food emptying from the stomach without any evidence of mechanical obstruction. The majority of cases are idiopathic. Patients need to be diagnosed properly by formal testing, and the evaluation of the severity of the gastroparesis may assist in guiding therapy. Initially, dietary modifications are encouraged, which include fre...

The regulation of gastrointestinal motility mainly involves the smooth muscle, neural (extrinsic and intrinsic), and hormonal elements, the glial cells, and the interstitial cells of Cajal. An orchestrated function of all these components is required for the appropriate propulsive movement of the food in the gastrointestinal tract. Gastroparesis, a pathological slowing-down of gastric emptying,...

Abdominal pain and vomiting are common presentations to the emergency medical ward. Management of recurrent abdominal can be difficult, especially in patients who have diabetes. People with diabetes present that cause a diagnostic dilemma. Are symptoms due an acute or chronic complication their other causes? In also use cannabis, further challenges arise as diabetic gastroparesis cannabinoid hy...

poorly controlled type 2 diabetes mellitus was admitted to hospital following 3 weeks of nausea and nocturnal vomiting, and weight loss of 4 kg. On physical examination, she had a soft abdomen and a palpable gallbladder. Abdominal radiography using water-soluble oral contrast medium (Figure 1) showed pooling in the pelvic region. Computed tomography performed immediately after radiography showe...

BACKGROUND Gastroparesis has a number of etiologies. The main ones are secondary to a complication from diabetes mellitus, related to post vagotomy or post gastric surgical resections, or idiopathic when the etiology is unclear. Gastroparesis secondary to a demyelinating disease of the brain is unusual. CASE PRESENTATION A 22-year-old woman was referred for acute onset of intractable nausea a...

Diabetic gastroparesis is characterised by a delay in gastric emptying after a meal in the absence of a mechanical gastric outlet obstruction. Chronic intermittent intravenous insulin therapy (CIIIT) involves delivering insulin intravenously in an infusion over a 6-12 hour period in a pulsatile fashion adjusting the dosages based on frequent blood sugar monitoring. The aim of the study was to e...

Chronic gastroparesis and CIP are debilitating disorders that are difficult to treat with currently available therapies. Failure of proper migration and differentiation of enteric neurons or ICC can result from specific genetic mutations and lead to phenotypes of CIP with or without concomitant gastroparesis. Intestinal dysfunction in diabetes may reflect a depletion of NO production (and perha...