BACKGROUND AND AIM Clinical features of patients who develop gastric cancer after successful eradication of Helicobacter pylori are still unclear. We attempted to identify host factors associated with the discovery of gastric cancer, including changes in the background gastric mucosa in patients with atrophic gastritis. METHODS We enrolled 101 patients (59 men, 42 women; mean age 56.0 years) ...

Gastritis adalah salah satu masalah penyakit saluran pencernaan yang paling sering terjadi dapat bersifat akut atau kronis pada mukosa lambung. Gaya hidup tidak sehat mengakibatkan satunya gastritis. Tujuan dalam penelitian ini untuk mengetahui hubungan antara pengetahaun dengan gaya pencegahan kekambuhan gastritis mahasiswa Akper Pemerintah Kabupaten Ngawi. Penelitian kuantitatif pendekatan Ko...

Background. Since gastrointestinal stromal tumor (GIST) is a mesenchymal submucosal tumor, the endosonographic, CT, and MRI features of gastric GISTs have been widely investigated. However, the GIST-bearing gastric mucosa status has not been reported. Objective. To characterize the GIST-bearing gastric mucosa status in terms of the degree of inflammation and atrophy, assessed endoscopically. Su...

it is now well known that chronic atrophic gastritis may occur in patients who do not have Addisonian pernicious anaemia, and that the histological appearance of the gastric mucosa in patients with and without pernicious anaemia may be indistinguishable. In fact there is no pathognomonic histological gastric lesion in pernicious anaemia (Magnus, 1958; Williams, Coghill, and Edwards, 1958). Furt...

BACKGROUND Infection with Helicobacter pylori triggers a chronic gastric inflammation that can progress to atrophy and gastric adenocarcinoma. Polarization of macrophages is a characteristic of both cancer and infection, and may promote progression or resolution of disease. However, the role of macrophages and their polarization during H. pylori infection has not been well defined. METHODOLOG...

Gastric intestinal metaplasia, an intermediate lesion in the development of intestinal-type gastric cancer, is observed in the milieu of long standing non-atrophic gastritis and atrophic gastritis. Most patients with intestinal metaplasia remain asymptomatic unless cobalamin deficiency occurs secondary to loss of glands (that produce intrinsic factor and acid). Genetic events that predispose to...

A population-based screening for detection of early cancers evaluated the prevalence of precancerous gastric lesions in an area in Shandong province, China, with one of the world's highest rates of stomach cancer. A total of 3433 residents aged 35 to 64 yr received gastroscopical examinations with biopsies taken from standard locations. Chronic atrophic gastritis was nearly universal; less than...

Background/Aims Atrophic gastritis is considered a premalignant lesion. We aimed to evaluate the risk factors for gastric tumorigenesis in underlying mucosal atrophy. Methods A total of 10,185 subjects who underwent upper gastrointestinal endoscopy between 2003 and 2004 were enrolled in this retrospective cohort study. Follow-up endoscopy was performed between 2005 and 2014. Atrophic gastriti...

it is now well known that chronic atrophic gastritis may occur in patients who do not have Addisonian pernicious anaemia, and that the histological appearance of the gastric mucosa in patients with and without pernicious anaemia may be indistinguishable. In fact there is no pathognomonic histological gastric lesion in pernicious anaemia (Magnus, 1958; Williams, Coghill, and Edwards, 1958). Furt...