The use of fumaric acid esters in the treatment of psoriasis was first proposed in 1959. In the 1980s, more standardized oral preparations of fumaric acid esters were developed, containing dimethylfumarate and monoethylfumarate as the main compounds. In 1994, the drug was approved for the treatment of psoriasis in Germany, and since then it has become the most commonly used systemic therapy in ...

In the crystal structure of the title cocrystal, 2C(7)H(7)NO·C(4)H(4)O(4), the complete fumaric acid mol-ecule is generated by a crystallographic inversion centre. The two components of the cocrystal are linked by an O-H⋯N hydrogen bond.

This reaction is analogous to the aspartase reaction and to the enzymic condensation of arginine and fumaric acid (2). In this paper a more detailed characterization of the adenylosuccinase reaction and the product of the reaction, adenylosuccinic acid, is reported. A synthesis of the aglycone of adenylosuccinic acid, 6-succinoaminopurine, from aspartic acid and 6chloropurine, which confirms th...

Fumaric acid is a promising monomer to obtain biomass-based polyesters and polyamides, it mainly produced by fungi of the Rhizopus genus in medium high titters. The use glucose, main component starchy cellulosic food waste, as carbon source, together with low-nitrogen source concentration, route reduce process costs. In this work, effects nitrogen carbonate sources on arrhizus NRRL 1526 morphol...

The lower content of organic acids in grape berries due to global warming, and therefore high pHs, is forcing winegrowers acidify must or wine preserve their microbiological stability physico-chemical equilibrium. Acidification essential avoid damageable consequences on the colour sensory quality wines. Of possible modes acidification, chemical acidification still most common one used by OIV co...

In the crystal structure of the title compound, C(6)H(9)N(2) (+)·0.5C(4)H(2)O(4) (2-)·0.5C(4)H(6)O(4), the fumarate dianion and fumaric acid mol-ecule are located on inversion centres. The 2-amino-5-methyl-pyrimidinium cation inter-acts with the carboxyl-ate group of the fumarate anion through a pair of N-H⋯O hydrogen bonds, forming an R(2) (2)(8) ring motif. These motifs are centrosymmetricall...