The growth of interest in endocrine aspects of oncogenesis and cancer control is reflected in reports originating from a number of recent special conferences and has led to a massive literature. A large portion of these publications is concerned with studies of experimental tumor induction in the endocrine glands and their target organs (23, 62, 67, 72, 98, 124, 129, 150, 195). Recently, intere...

Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate endocrine disorders in patients with Beta-thalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this des...

The growth of interest in endocrine aspects of oncogenesis and cancer control is reflected in reports originating from a number of recent special conferences and has led to a massive literature. A large portion of these publications is concerned with studies of experimental tumor induction in the endocrine glands and their target organs (23, 62, 67, 72, 98, 124, 129, 150, 195). Recently, intere...

Cells communicate with each other through molecular messengers, the hormones. The simple definition of a hormone as an intercellular messenger is much more inclusive than the original one, which limited the hormones to substances produced by specialized multicellular organs —the glands—that circulated in blood and acted on distant target organs. This simplification allowed single cells to be co...

Neuroendocrine tumours belong to a heterogeneous family of neoplasms, originating in endocrine glands (such as the pituitary, parathyroid or the neuroendocrine adrenal glands), in endocrine islets (within the thyroid or pancreas) as well as in endocrine cells dispersed between exocrine cells throughout the digestive or respiratory tracts. The clinical behaviour of neuroendocrine tumours is vari...

results the main pathological finding observed in the prostrate and seminal vesicle glands, using light microscope, revealed congestion in the connective tissue and vacuolization in the secretory units of epithelial cells and epithelium rupture at 50 and 100 µg/kg doses of bpa. ultrastructure study showed vacuolization of mitochondria, condensation of nuclei and disappearance of nucleus in the ...

The endocrine system may be the target of different types of trauma with varied consequences. The present article discusses trauma of the hypothalamic-pituitary axes, adrenal glands, gonads, and pancreas. In addition to changes in circulating hormone levels due to direct injury to these structures, there may be an endocrine response in the context of the stress caused by the trauma.

Plasmalemma vesicle protein-1 (PV-1) is an integral membrane protein associated with endothelial cell caveolae and fenestrae. Since endocrine glands are enriched with fenestrated endothelium, we examined the distribution of PV-1 mRNA and protein in endocrine glands and determined its cellular localization. A single transcript was detected by RT-PCR in all endocrine glands examined. A synthetic ...

The authors conducted a review of the major aspects of progression of knowledge about the surgical treatment of hyperparathyroidism. Through literature review, we analyzed articles on the history of the evolution of anatomical, physiological, pathological and surgical knowledge of the parathyroid glands. Because of their unique anatomical features, the parathyroid glands were the last of the en...

The pancreas is an organ that actually consists of two glands: one exocrine and one endocrine gland. The glandular epithelium is a specialized epithelial tissue which produces and excretes substances to control our bodily functions. The exocrine gland secretes its fluids via ducts (into the intestinal lumen), while the endocrine gland secretes its substances via the extracellular space into the...