PURPOSE The aim of this study was to investigate acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and antityrosinase activities of extracts from ten Piper species namely; P. caninum, P. lanatum, P. abbreviatum, P. aborescens, P. porphyrophyllum, P. erecticaule, P. ribesioides, P. miniatum, P. stylosum, and P. majusculum. METHODS Anticholinesterase and antityrosinase activities were e...

Certain observations have been reported according to which complications in association with gold therapy in rheumatoid arthritis would seem to be inversely proportional to the erythrocyte sedimentation rate (Goldie, 1939; Ellman and others, 1940; Lawrence, 1953). This has been explained on the basis that a high E.S.R. is generally seen in the active exudative stage of the disease, and that the...

Besides cold-steel and laser instruments, the use of radiofrequency (RF) devices in transoral microsurgery is getting increasing popularity mainly due to its minimal thermal effect on the collateral soft tissue. Authors summarize their surgical technique, results, and experience gained with RF applied during laryngeal interventions at the Department of Otorhinolaryngology, Head and Neck Surgery...

Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are the key enzymes in pathogenesis of Alzheimer's disease (AD), which is characterized by a deficit in central cholinergic transmission. In the current study, AChE and BChE inhibitory activities of seven coumarin derivatives [umbelliferone (1), 4-methylumbelliferone (2), 4-hydroxycoumarin (3), scopoletin (4), 8-methoxypsoralen (5), b...

Though the association between pulmonary fibrosis and scleroderma has been recognized for over 60 years (Finlay, 1891), it is only within the last decade that cyst formation has been recognized as a possible part of the lung condition, following the detailed description by Getzowa (1945) of the morbid anatomy and histology of two fatal cases. Since then a considerable literature has arisen. Som...

BACKGROUND Radiofrequency surgery is a method of utilizing high frequency (3.8 to 4MHz) radio wave energy to incise, excise, or coagulate tissues. Radiofrequency (RF) is a relatively new modality that is being used for ano-rectal surgeries with increasing frequency. As the RF energy is applied, frictional heating of tissues results, with cell death occurring at temperatures between 60 and 100 d...

A polymer-assisted solution-phase (PASP) synthesis of lead structure analogues ready for biological testing without the demand for chromatographic purification is described. Carboxylic acids are coupled to the Kenner or Ellman safety catch linker, respectively, activated by methylation or cyanomethylation and subsequently transferred to the 2'-amino group of the 2'-amino-2'-deoxyadenosine scaff...

OF THE DISSERTATION The Use of Arti cial Intelligence to Improve the Numerical Optimization of Complex Engineering Designs by Mark A. Schwabacher Dissertation Directors: Thomas Ellman and Andrew Gelsey Gradient-based numerical optimization of complex engineering designs promises to produce better designs rapidly. However, such methods generally assume that the objective function and constraint ...

The introduction of ultralow volume (ULV) application of the organophosphate pesticide Fenitrothion in grain terminals presents a risk to workers of skin contact with concentrate. Blood testing, by the Ellman method, of a group of five grain terminal workers working on grain treatment showed a lowering of mean red blood cell cholinesterase (RBC ChE) activity to 23 units/gm Hb (normal value 28-4...

Methods Our study included six patients with acquired infection from central catheter; the microbial pathogens were Streptococcus viridans (n = 3) and Staphyloccocus aureus (n = 3). The diagnosis of IE was based on positive blood culture (2 positive cultures of blood samples drawn > 12 hours), evidence of endocardial involvement (positive ECHO), measuring raised erythrocyte sedimentation rate a...