In her initial research, Elizabeth D. Hay studied amphibian limb regeneration, but later switched her focus, and for the remainder of her career addressed the role of the extracellular matrix (ECM) in regulating embryonic morphogenesis. Much of that work used the embryonic chick corneal epithelial model. This review highlights many of the discoveries that she made using this model. Hay was the ...

This study’s purpose was to propose a hybrid model based on expectation–confirmation model (ECM), technology acceptance model (TAM), and updated DeLone & McLean information system (IS) success model to examine whether quality factors as the antecedents to user beliefs affected users’ continuance intention of the digital library. Sample data for this study were collected from students enrolled i...

In this paper we consider a simple continuous model to describe cell invasion, incorporating the effects of both cell-cell adhesion and cell-matrix adhesion, along with cell growth and proteolysis by cells of the surrounding extracellular matrix (ECM). We demonstrate that the model is capable of supporting both noninvasive and invasive tumour growth according to the relative strength of cell-ce...

Strong magnetic activity in ultracool dwarfs (UCDs, spectral classes later than M7) have emerged from a number of radio observations, including the periodic beams. The highly (up to 100%) circularly polarized nature of the emission point to an effective amplification mechanism of the high-frequency electromagnetic waves – the electron cyclotron maser (ECM) instability. Several anisotropic veloc...

The expectation-confirmation model (ECM) has been applied to investigate the satisfaction with and continuance of information technology (IT) after its adoption. However, the ECM assumes that the satisfaction-continuance relationship is linear. In the electronics market, however, such a linear relationship may be susceptible to the influence of new variants unique to the Internet. In addition, ...

New trends and the effect of key factors influence the quality of the holes produced by ECM processes. Researchers developed a fuzzy logic controller by adding intelligence to the ECM process. Maintaining optimum ECM process conditions ensures higher machining efficiency and performance. This paper presents the development of a fuzzy logic controller to add intelligence to the ECM process. An e...

MT1-MMP is a potent invasion-promoting membrane protease employed by aggressive cancer cells. MT1-MMP localizes preferentially at membrane protrusions called invadopodia where it plays a central role in degradation of the surrounding extracellular matrix (ECM). Previous reports suggested a role for a continuous supply of MT1-MMP in ECM degradation. However, the turnover rate of MT1-MMP and the ...

Reciprocal mechanical interactions between cells and the extracellular matrix (ECM) are thought to play important instructive roles in branching morphogenesis. However, most studies to date have failed to characterize these interactions on a length scale relevant to cells, especially in three-dimensional (3D) matrices. Here we utilized two complementary methods, spatio-temporal image correlatio...