A case is presented of a woman who developed obstructive jaundice secondary to dysplastic mucinous papillomatosis two years after she had undergone cholecystectomy and exploration of the common bile duct. The gall bladder was dysplastic. It is suggested that the dysplastic glands removed from the common bile duct at the second operation either represented seedlings from dysplastic areas of the ...

reelin is an extracellular matrix neuroprotein which plays important roles during development and maturation of cerebellum. in the postnatal cerebellum, reelin is synthesized by cerebellar granule cells and secreted to extracellular matrix. this secreted protein modulates adult synaptic function, neurotransmitter release and regulates plasticity. exercise has beneficial effects on central nervo...

introduction: previous studies have suggested that the cerebellum is a primary site of motor learning. the cerebellar cortex has a particular glial architecture with large astroglial cells. in addition, more recent works have revealed that astrocytes play a more active role in neuronal activity. the aim of this study was to evaluate the number of astrocytes in the molecular layer of rat's ...

background: interferon beta-la and -1b have been increasingly used for the treatment of multiple sclerosis (ms). the most frequent systemic adverse effects are flu-like symptoms. laboratory abnormalities include asymptomatic leukopenia and elevated hepatic transaminases. myelodysplastic syndrome (mds) refers to a spectrum of hematological disorders which can occur in different situations. sever...

OBJECTIVES To determine the development rate of hepatocellular carcinoma and survival of patients diagnosed to have regenerative, and low-grade and high-grade dysplastic liver nodules. DESIGN Retrospective descriptive study. SETTING Acute public hospital, Hong Kong. PATIENTS Patients with non-malignant liver nodules confirmed by imaging-guided liver biopsy between January 1997 and Decembe...

BACKGROUND Acetabular dysplasia is a major predisposing factor for development of hip osteoarthritis (OA), and may result from alterations to chondrolabral loading. Subject-specific finite element (FE) modeling can be used to evaluate chondrolabral mechanics in the dysplastic hip, thereby providing insight into mechanics that precede OA. OBJECTIVE To evaluate chondrolabral contact mechanics a...

BACKGROUND AND PURPOSE The cause and clinical significance of residual dysplastic vessels after surgery for brain arteriovenous malformations (AVM) are unclear. We studied predictors and frequency of residual dysplastic vessels on cerebral angiography after AVM surgery. METHODS The 240 prospectively enrolled surgical patients from the New York AVM Databank underwent 269 AVM-related surgical p...