The mechanism of hypertension-induced renal fibrosis is not well understood, although it is established that high levels of angiotensin II contribute to the effect. Since β-catenin signal transduction participates in fibrotic processes, we evaluated the contribution of β-catenin-dependent signaling pathway in hypertension-induced renal fibrosis. Two-kidney one-clip (2K1C) hypertensive rats were...

Received: Revised: Accepted: 2013–11–17 2014–02–28 2014–03–04 The study was conducted to determine the infection rate of helminths in peafowls and to evaluate the comparative efficacy of two broad spectrum anthelmintics. For this purpose, fecal samples of 87 different breeds of peafowls were collected and tested for the presence of helminths. Fecal samples were examined by direct smear and cent...

Olanzapine long-acting injection (OLAI) is a crystalline salt composed of olanzapine and pamoic acid, which permits a depot intramuscular formulation of olanzapine. The half-life of olanzapine pamoate is 30 days, and its steady state is reached approximately at 12 weeks. Oral supplementation of olanzapine is not required during OLAI initiation, according to Eli Lilly recommendations, although a...

Tnis(p-aminophenyl)carbonium pamoate (2 lots) was administered as drug-diet for an 18-month period to male and female albino rats (Holtzman source) . Both lots of compound were prepared from the chloride salt, one from an approximately 98.6 % pure sample, and the other from a highly purified and apparently homogenous sample. There was a marked increase in total tumor incidence in the treated fe...

Oesophagostomum bifurcum has recently been recognized as a common parasite of man in northern Togo and in Ghana. In a preliminary trial several anthelmintics were evaluated in the treatment of mixed Oesophagostomum and hookworm infections. Diagnosis was based on faecal culture, since the eggs of Oesophagostomum and hookworm cannot be distinguished morphologically. Of the anthelmintics tested, a...