We derive the Cramér-Rao lower bounds (CRB) for parametric estimation of the number-weighted particle size distribution (PSD) from multiangle Dynamic Light Scattering (DLS) measurements. The CRB is a useful statistical tool to investigate the optimality of the PSD estimators. In the present paper, a Gaussian mixture (GM) model of the multimodal PSD is assumed and the associated Fisher informati...

In an orthogonal-frequency-division multiplex (OFDM) system, the problem of sampling clock synchronization and channel estimation is analyzed. In such systems, when the number of sub-carriers is large, a sampling clock frequency mismatch between the transmitter and the receiver dramatically degrades the performance. Obviously, the channel-impulse response is unknown at the receiver and also nee...

Reconstructing a signal from squared linear (rankone quadratic) measurements is a challenging problem with important applications in optics and imaging, where it is known as phase retrieval. This paper proposes two new phase retrieval algorithms based on non-convex quadratically constrained quadratic programming (QCQP) formulations, and a recently proposed approximation technique dubbed feasibl...

The establishment and maintenance of epithelial cell polarity is essential throughout the development and adult life of all multicellular organisms. A key player in maintaining epithelial polarity is Crumbs (Crb), an evolutionarily conserved type-I transmembrane protein initially identified in Drosophila. Correct Crb levels and apical localization are imperative for its function. However, as is...

This paper considers the Cramer-Rao lower Bound (CRB) for the source localization problem in the near field. More specifically, we use the exact expression of the delay parameter for the CRB derivation and show how this ‘exact CRB’ can be significantly different from the one given in the literature and based on an approximate time delay expression (usually considered in the Fresnel region). Thi...

We consider narrowband angle of arrival estimation in nonGaussian (NG) noise channels, such as arises in some indoor and outdoor mobile communications channels. We develop a general expression for the Cramer-Rao bound (CRB) for direction nding using arrays for deterministic signals plus iid non-Gaussian noise, generalizing the Gaussian CRB. The CRBs for the noise and direction parameters decoup...

A new interpretation for the second peak of T Coronae Borealis (T CrB) outbursts is proposed based on a thermonuclear runaway (TNR) model. The system consists of a very massive white dwarf (WD) with a tilting accretion disk and a lobe-filling red-giant. The first peak of the visual light curve of T CrB outbursts is well reproduced by the TNR model on a WD close to the Chandrasekhar mass (MWD ∼>...

After providing an extension of the Slepian–Bangs formula for general noncircular complex Gaussian distributions, this paper focuses on the stochastic Cramér–Rao bound (CRB) on direction-of-arrival (DOA) estimation accuracy for noncircular sources. We derive an explicit expression of the CRB for DOA parameters alone in the case of noncircular complex Gaussian sources by two different methods. O...

This paper concerns the Cramer-Rao lower bound (CRB) for the data-aided (DA) timing and/or phase recovery, i.e., the synchronization parameter acquisition is aided by a training sequence known to the receiver. For the DA parameter estimation, the CRB typically varies with the training sequence. This indicates that different training sequences offer fundamental different performance. In this man...

BACKGROUND Tunnelled catheters are used for dialysis in over 25% of haemodialysis (HD) patients and are a major risk factor for bacteraemia. HIV-positive patients may be at particularly increased risk of catheter-related bacteraemia (CRB) due to their immunocompromised state. The present case-controlled study compared catheter-related bacteraemia with HIV-positive and HIV-negative haemodialysis...