نتایج جستجو برای: chlorambucil

تعداد نتایج: 2068  

2013
Iwona Rospond-Kubiak Jarosław Kocięcki Marcin Stopa

INTRODUCTION Ocular lymphomas account for five to 10 percent of all extra-nodal lymphomas. Primary uveal lymphoma is quite a rare entity and usually unilateral. We present a case of a primary uveal lymphoma with conjunctival and orbital extension, successfully managed with oral chlorambucil. CASE PRESENTATION A 71-year-old Caucasian man presented to our facility with visual loss in his only f...

Journal: :British Journal of Ophthalmology 1976

2013
Andrew Howman Tracey L Chapman Maria M Langdon Caroline Ferguson Dwomoa Adu John Feehally Gillian J Gaskin David RW Jayne Donal O'Donoghue Michael Boulton-Jones Peter W Mathieson

BACKGROUND Membranous nephropathy leads to end-stage renal disease in more than 20% of patients. Although immunosuppressive therapy benefits some patients, trial evidence for the subset of patients with declining renal function is not available. We aimed to assess whether immunosuppression preserves renal function in patients with idiopathic membranous nephropathy with declining renal function....

2015
Brian T Hill Matt Kalaycio

Chronic lymphocytic leukemia (CLL) is a hematologic malignancy derived from a clonal population of mature B-lymphocytes characterized by relatively low CD20 antigen expression. Although the disease often takes an indolent course, the majority of patients will eventually require therapy. Standard treatment for medically fit patients includes purine analogs and/or alkylating agents in addition to...

Journal: :Lancet 2003
K M Ardeshna P Smith A Norton B W Hancock P J Hoskin K A MacLennan R E Marcus A Jelliffe G Vaughan Hudson D C Linch

BACKGROUND Neither chemotherapy with a single-alkylating agent nor aggressive combination chemotherapy cures advanced stage low-grade non-Hodgkin lymphomas, even when combined with radiotherapy. Our aim was to compare administration of immediate chlorambucil treatment with a policy of delaying chlorambucil until clinical progression necessitated its use, in asymptomatic patients with advanced-s...

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