نتایج جستجو برای: bone morphogenetic protein 2

تعداد نتایج: 3672045  

2007
Liming Xu Ryoya Takahashi Hidemitsu Harada Akiyoshi Taniguchi

Epithelial-mesenchymal interactions play an important role in the control of ameloblasts and odentoblasts differentiation, and the bone morphogenetic proteins (BMPs) are known factors that regulate the differentiation of ameloblasts. We examined the effect of BMP-2 on the expression of the enamel matrix protein genes at the dental epithelial cell line. BMP-2 induced a 3to 4-fold increase in ame...

Journal: :Canadian journal of physiology and pharmacology 2012
Marcel Haversath Isabelle Catelas Xinning Li Tjark Tassemeier Marcus Jäger

Osteoarthritis and lesions to cartilage tissue are diseases that frequently result in impaired joint function and patient disability. The treatment of osteoarthritis, along with local bone defects and systemic skeletal diseases, remains a significant clinical challenge for orthopaedic surgeons. Several bone morphogenetic proteins (BMPs) are known to have osteoinductive effects, whereof BMP-2 an...

Journal: :Journal of cell science 2004
Martin F Pera Jessica Andrade Souheir Houssami Benjamin Reubinoff Alan Trounson Edouard G Stanley Dorien Ward-van Oostwaard Christine Mummery

Human embryonic stem cells differentiate spontaneously in vitro into a range of cell types, and they frequently give rise to cells with the properties of extra-embryonic endoderm. We show here that endogenous signaling by bone morphogenetic protein-2 controls the differentiation of embryonic stem cells into this lineage. Treatment of embryonic stem cell cultures with the bone morphogenetic prot...

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