La excavación arqueológica realizada en el barrio del Seminario ha permitido conocer por primera vez cómo era físicamente la Cuirassa de Lleida, una las juderías más importantes Corona Aragón, que paso tiempo borró trama urbana ciudad. Hemos intentado, dentro lo posible, relacionar los restos inmuebles descubiertos con fuentes documentales conocidas, hasta obtener un plano aproximado donde se s...

The chemical structures of AT2433-A1 (2), AT2433-A2 (3), AT2433-B1 (4) and AT2433-B2 (5) were elucidated by degradation and spectroscopic studies. Compounds 2-5 are disaccharides closely related to rebeccamycin. The aglycone in 2 and 3 was determined to be 6-N-methyl-11-chloro-5H-indolo[2,3-a]pyrolo[3,4-c]carbazole and in 4 and 5 it was determined to be 6-N-methyl-5H-indolo[2,3-a]pyrolo[3,4-c]c...

Abstract Background Intravenous artesunate is the World Health Organization–recommended first-line treatment for severe malaria worldwide, but it still not fully licensed in Europe. Observational studies documenting its safety and efficacy imported are thus essential. Methods We prospectively collected clinical epidemiological features of 1391 artesunate-treated patients among 110 participant c...

Background and Aim: Both Budd-Chiari syndrome (BCS) portal vein thrombosis (PVT) have been linked to various prothrombotic (PT) conditions. The PT profile in Asians is different from the West there are no nationwide epidemiological surveys India. Hence, present meta-analysis was aimed at analyzing prevalence of acquired hereditary thrombophilia among Indian patients with non-cirrhotic PVT BCS. ...

Although the glycoprotein MFG-E8 (milk fat globule-epidermal growth factor-factor 8) has been investigated extensively as an anti-inflammatory and homeostatic molecule, a possible role in bone homeostasis and disease was not addressed until recently. Our group has now shown that MFG-E8 is expressed by human and mouse osteoclasts and regulates their differentiation and function (Abe et al., J Im...

Objective: Acute poisoning is considered as an important health problem leading to admission of children. Also, the epidemiologic surveillance specific for each country is necessary. Therefore, we conducted this study to obtain the epidemiological information on poisoning in Nemazee Hospital, a referral center in South of Iran. Methods: In this cross sectional study, we determined age, sex, pre...

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