background: inflammatory bowel disease unclassified (ibdu) is considered to be an aberrant immune response with loss of tolerance to many antigens. objective: this paper tries to address whether there is any value to test for auto-antibodies in such patients. methods: 60 patients with inflammatory bowel disease unclassified participated in the study. auto-antibodies to nuclear antigen, intestin...

Inflammatory cytokines have a role in triggering cell signals colorectal cancer. They increase signaling pathways into cells via the Janus kinase pathway (JAK) - signal transducer and activator of transcription (STAT) -suppressor cytokine (SOCs) JAK-STAT. SOCs2 protein is cytoplasmic that can inhibit activation JAK-STAT so it prevents cascade nucleus. This thought to decreased adenocarcinoma co...

The presence of immunoglobulin G receptors in human fibroblasts infected with human cytomegalovirus (CMV) resulted in a nonspecific cytoplasmic reaction in the indirect fluorescent-antibody test. Both CMV antibody-positive and antibody-negative sera from human or other animal species produced the cytoplasmic reaction. The substitution of a simian CMV strain for the human virus successfully elim...

A 70-year-old man presented with proteinuria, microscopic hematuria, and an increased level of serum creatinine. systemic workup revealed that the patient had bronchogenic carcinoma anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis concurrently. Despite increase in cumulative number publications on paraneoplastic glomerulopathies, awareness link between cancer ANCA-assoc...