A number of antineoplastic drugs are used to combat with different types of cancer which have also shown to be mutagenic in various test systems. Various antineoplastic drugs such as cisplatin, cyclophosphamide, Tamoxifrn Genecitabine and Paclitaxel etc have shown to be clastogenic effects in various test systems (Garrone et al., 1993; Takeda et al., 2001; Padmalatha Rai and Vijaylakhmi, 2001; ...