The present trial aimed to investigate the effects of pioglitazone on the serum level of asymmetric dimethylarginine (ADMA), a marker of endothelial function, and some indices of inflammation and glucose and lipid metabolism in nondiabetic metabolic syndrome patients. 104 eligible participants (57% female; age between 20 and 70) were enrolled in a double-blind placebo-controlled trial and were ...

INTRODUCTION This study was designed to scientifically evaluate the effects of an aqueous extract of Muntingia calabura L. (M. calabura), a medicinal herb, on isoproterenol-induced myocardial infarction (MI) in rat models. METHODS Six groups of Wistar albino rats, each comprising six animals, were selected for this study. Group I served as a control, Group II rats were given isoproterenol (20...

The effect of an acyclic synthetic retinoid analogue NIK-333, on the restoration of liver mass and recovery of liver function after 70% partial hepatectomy, was compared with natural retinoids in rats in vivo. NIK-333 (0.4 mg/kg/day, p.o.)- and all-trans-retinoic acid (ATRA: 4 mg/kg/day, p.o.)-treated rats showed an approximately 1.3- and 1.2-fold increase in liver-to-body weight ratio, respect...

The Objective For The Present Study Is To Investigate Of The Effects Of Melatonin (Mel) On Serum Leptin, Testosterone, Liver Function Test Parameters In Control And Pinealectomized (Pinx) Rats. Thirty Seven Adult Male Rats Were Used In This Study. The Experimental Rats Were Divided Into Six Groups, And The Treatments Were Continued For Six Weeks As The Following: Group 1: Control Rats. Group 2:...

AIM The objective of this study was to correlate laboratory tests during the evolution of dengue fever, comparing frequencies between the different clinical forms in order to use test results to predict the severity of the disease. METHODS This is an observational, descriptive and retrospective study of 154 patients with clinical and serological diagnoses of dengue fever who, in the period fr...

Liver stiffness was measured by transient elastography (FibroScan) in 228 consecutive patients with chronic viral hepatitis, with (115) or without cirrhosis (113), to study its correlations with serum transaminases [alanine aminotransferase (ALT)], fibrosis stage and surrogate noninvasive markers of fibrosis (APRI, FORNS, FibroTest and hyaluronic acid). The dynamic profiles of serum transaminas...

background: tramadol narcotic drugs or epoxied artificial categories is weaker than morphine and stronger than ibuprofen and acetaminophen drug. the aim of this study was to investigate the effect of oral tramadol on some liver enzymes in the rat. materials and methods: in this study, 60 male wistar rats were randomized into three groups (one control group, and experimental groups of 1, and 2)....

The existence of a glutamic acid racemase activity in Lactobacillus arabinosus has been reported by Narrod and Wood (1) and by Ayengar and Roberts (2). As has been pointed out by Meister (3) these observations with dried cell preparations would not exclude a mechanism for glutamic acid racemization in which alanine racemase is coupled with n-glutamic acid-nalanine transaminase and n-glutamic ac...