Insulin is mainly known for its peripheral effects on the metabolism of glucose, fats, and proteins. Following the discovery of insulin by Banting and Best in 1921, major research works focused on the role of insulin in the peripheral tissues (liver, muscle and adipo‐ cytes) in regulating glucose homeostasis. During the last two decades, evidence has accu‐ mulated that insulin also exerts impor...

In the February issue of the Indian Medical Gazette, 1889, S. Coull Mackenzie, Police Surgeon of Calcutta, published an account of eight cases of saponification observed by him during his nine years of medico-legal work in that city. In the April issue of the same journal for 1897 Dr. George H. F. Nutall published a paper under the title " Has adipocere been observed in India?" in which he poin...

Adipo(cyto)kines are mostly produced by adipose tissue and orchestrate the adverse impact of excess adiposity on cardiovascular risk. Adipokines also contribute importantly to the pathophysiology of rheumatoid arthritis. Congruent with data reported in previous investigations, Kang and colleagues report in this issue of Arthritis Research & Therapy that adipokine concentrations are further asso...