UNLABELLED An object-oriented software system is described for estimating internal emitter absorbed doses using a set of computer modules operating within a personal computer environment. The system is called the Radionuclide Treatment Planning and Absorbed Dose Estimation System (RTDS). It is intended for radioimmunotherapy applications, although other forms of internal emitter therapy may als...

introduction: patients administered with a therapeutic dose of 131i for thyroid cancer treatment are potential sources of unacceptably high radiation exposure to other individuals, particularly the patient's immediate family members. the aim of this study is to investigate effects of early liothyronine consumption after radio-iodine therapy on accumulated dose and exposure rate in patients with...

Topical iodine forms are used for infected and necrotic pressure ulcers. Despite antimicrobial advantages several potential disadvantages were observed with controversial results. To clarify the controversy, the reactivity of povidone-iodine (PI) sugar ointment and cadexomer-iodine (CI) ointment toward biological components was investigated. L-Tyrosine as a component of proteins and egg lecithi...

H arold L. Atkins, MD, was presented with the LoevingerBerman Award for excellence in the field of internal dosimetry on Sunday, June 15, at the SNM Annual Meeting in New Orleans, LA. The award was established in 1999 by the Medical Internal Radiation Dose (MIRD) Committee in honor of Robert Loevinger and Mones Berman, who formulated the MIRD schema for internal dose calculations. The award is ...

Therapy with 90Y-microspheres is emerging as a mainstream treatment modality in the management of patients with primary and metastatic liver cancer (1,2). The technique involves the administration of 90Y-microspheres into the hepatic artery, which is accessed via the transfemoral route or through a hepatic arterial infusion port or pump. The technique was first introduced by Ariel, who also rep...

  Introduction: Radioactive materials deliver internal radiation dose to patients in nuclear medicine. Manual internal radiation dose assessment is a complicated method. Introduction of a simple dose calculation software is the main goal of the present study. Methods: Using the best current data in internal dose calculation (S-Factors) recommended by ICRP and by cons...

The manuscripts included in this special issue of Cancer Biotherapy & Radiopharmaceuticals highlight current data and theoretical foundations regarding dose–response relationships related to radionuclide therapy kidney toxicity. With the use of the kidney dosimetry model presented in MIRD 19,1 these experimental and clinical data, when correlated with accurate regional dose information, may pro...

Previously reported models for radioiodine in ruminants cannot account for the effect of variations in stable iodine intake including large countermeasure doses of stable iodine on the transfer of radioiodine to goat milk. A metabolically based model of radioiodine transfer in goats has been parameterised using new experimental data on the effect of countermeasure doses of stable iodine on radi...

Iodine sorption by polyurethane (PU) and melamine-formaldehyde (MF) foams was studied using both iodine sublimation and iodine solutions with hexanes and toluene. In the sublimation process, the diffusion kinetics was investigated and the interaction between iodine and PU foams was characterized by DSC, TGA, Raman spectroscopy and electrical conductivity measurements. In the solution process, t...