The most specific criterion for diagnosing neurosyphilis is a reactive CSF VDRL. Unfortunately, there are in Europe, including Poland small number of specialized laboratories for serological diagnosis of syphilis. Thus, CSF serology results are obtained with delay. Therefore, the decision on recommended therapy for neurosyphilis is taken on the basis of CSF basic tests. In this paper we attempt...

When pure individual synthetic lecithins became available for study (Baer and Kates, 1949, 1950), there was immediate interest in their possible use in cardiolipin antigens as substitutes for Pangborn lecithin. Rosenberg (1949) reported briefly on synthetic L-c-(dipalmitoyl)-lecithin in antigens for the Hinton, Kline, Rein-Bossack, VDRL, and Kolmer tests. He found that replacement of Pangborn's...

A collaborative study was designed to asses two freeze-dried human plasma preparations containing anti-Treponema pallidum antibodies, 05/132 and 05/122, for their suitability as international reference reagents for syphilis serology. Both preparations are intended as replacements of the first international standard (IS) for syphilitic serum antibodies (HS). Samples were tested by eight laborato...

OBJECTIVE To determine the seroreactivity of pregnant women to syphilis in order to justify the need for routine antenatal syphilis screening. METHODS A multicenter retrospective analysis of routine antenatal venereal disease research laboratory (VDRL) test results between 1 September 2010 and 31 August 2012 at three specialist care hospitals in south-east Nigeria was done. A reactive VDRL re...

INTRODUCTION Human papillomavirus (HPV) is one of the most common causes of sexually transmitted diseases (STD). The incidence of condyloma acuminata (CA) has increased in recent years. AIM To determine demographical features and serological test results of STD in patients with CA. MATERIAL AND METHODS A cross-sectional survey was conducted on 94 patients presenting to a dermatology clinic ...

OBJECTIVE To review the nature of the presentation of neurosyphilis, the value of diagnostic tests, and the classification of the disease. METHODS A retrospective review was carried out of the records of patients who had been identified as possible cases of neurosyphilis by a positive FTA-abs test in the CSF. The review extended over 10 years at a single hospital which served a population of ...

We evaluated an immunochromatographic point-of-care (POC) syphilis test in 712 pregnant women under field conditions in remote communities of the Amazon region (Brazil), and identified risk factors for syphilis. Women were screened by POC test using whole blood obtained by fingerprick, the fluorescent treponemal antibody absorption (FTA-Abs) test as the gold standard and the Venereal Diseases R...

A 47-year-old man with a history of human immunodeficiency virus (HIV) infection presented with an 8-month history of severe paroxysmal shooting pains in his legs, progressive difficulty in walking, tinnitus, and urinary incontinence. He had a fully suppressed HIV viral load and a CD4+ count of 400 cells per cubic millimeter while receiving antiretroviral therapy. The physical examination showe...