Local hyperadrenergic states after a random flap elevation mediated by humoral vasoconstrictors can lead to necrosis. This study aimed evaluate the effect of Botulinum Toxin A (BoNT-A) on reducing levels Norepinephrine (NE) as main vasoactive substance, well its additive with Vascular Endothelial Growth Factor (VEGF) in increasing viability flap. 28 Wistar Rats Caudally Based Modified McFarlane...