Uremic pruritus (UP) is a frequent and bothersome symptom in hemodialysis patients. Its etiology is not fully understood and that is why there is no specific treatment. The endocannabinoid system plays a role in many pathological conditions. There is reliable evidence on the association between cannabinoid system and pruritus. In our study, we aimed to evaluate whether genetic variations in the...

Introduction: Uremic xerosis with pruritus (UXP) is a chronic cutaneous complication among patients undergoing maintenance renal dialysis. level directly related severity or vice versa. may lead to discomfort and negative psychological effect. The ethiopathogenesis still unknown, Most of treatments are empirical, there no effective safe therapy. Emollient has not been enough improve quality lif...

Aims: Chronic kidney diseases effects make the pruritus prevalence in hemodialysis patients relatively high. Several studies have been conducted to determine effect of acupressure on complaints uremic pruritus. However, it is still debatable how relief complains regarding duration acupressure. This study aims identify effectiveness against based previous studies. Materials and Methods: An elect...

The beneficial effect of sunburn-spectrum ultraviolet (UVB) phototherapy on uremic pruritus was studied. Seven patients were treated twice weekly for 4 weeks with UVB to one half of the body and placebo phototherapy to the other half. All patients noted generalized improvement without localization of benefit to the UVB side, suggesting a systemic effect of UVB. A comparison of three schedules v...

Uremic pruritus remains a frequent concern for hemodialysis patients with the most frustrating and disabling symptoms. The word uremic may denote that patients suffer from acute renal injury. Hence it is preferred to use the recent term “chronic kidney disease associated pruritus” (CKDassociated pruritus). The prevalence of CKD-associated pruritus in patients ranges from 15%-90% in various stud...

INTRODUCTION Pruritus is one of the common problems in patients on hemodialysis. There are several causes for pruritus, and different treatment modalities are applied to control it. The aim of this study was to evaluate the therapeutic effect of capsaicin on pruritus, compared with placebo, in patients on hemodialysis. MATERIALS AND METHODS This randomized double-blinded cross-over clinical t...