نتایج جستجو برای: tricarboxylic acid

تعداد نتایج: 747504  

Journal: :Life 2021

The tricarboxylic acid cycle (TCA) is a series of chemical reactions used in aerobic organisms to generate energy via the oxidation acetylcoenzyme A (CoA) derived from carbohydrates, fatty acids and proteins. In eukaryotic system, TCA occurs completely mitochondria, while intermediates are retained inside mitochondria due their polarity hydrophilicity. Under cell stress conditions, can become d...

Journal: :Circulation 2007
Natalia Sorokina J Michael O'Donnell Ronald D McKinney Kayla M Pound Gebre Woldegiorgis Kathryn F LaNoue Kalpana Ballal Heinrich Taegtmeyer Peter M Buttrick E Douglas Lewandowski

BACKGROUND Transport rates of long-chain free fatty acids into mitochondria via carnitine palmitoyltransferase I relative to overall oxidative rates in hypertrophied hearts remain poorly understood. Furthermore, the extent of glucose oxidation, despite increased glycolysis in hypertrophy, remains controversial. The present study explores potential compensatory mechanisms to sustain tricarboxyli...

Journal: :The Journal of biological chemistry 1967
J K Bhattacharjee M Strassman

Accumulation of tricarboxylic acids related to lysine biosynthesis has been demonstrated in a yeast mutant, Ly,,, which requires lysine as a growth factor in synthetic medium but can substitute a-aminoadipic acid for the nutritional requirement of lysine. Both radioactive and nonradioactive intermediates have been isolated from the growth medium under appropriate conditions and have been identi...

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