نتایج جستجو برای: tissue inhibitor matrix metalloproteinase 1

تعداد نتایج: 3736052  

Journal: :The Journal of clinical investigation 1991
P E Desrochers J J Jeffrey S J Weiss

Human endothelial cells treated with either interleukin-1 beta, tumor necrosis factor-alpha, or phorbol myristate acetate secreted a metalloproteinase that hydrolyzed and inactivated the two major serine proteinase inhibitors (Serpins) found in plasma, alpha 1-proteinase inhibitor and alpha 1-antichymotrypsin. Surprisingly, the responsible metalloproteinase was identified as human interstitial ...

Journal: :International journal of oncology 2004
Fumihiko Kaneko Hidetsugu Saito Yoshimasa Saito Kanji Wakabayashi Nobuhiro Nakamoto Shinichiro Tada Hidekazu Suzuki Satoshi Tsunematsu Naoki Kumagai Hiromasa Ishii

We have demonstrated anti-proliferation and anti-metastasis effects of both interferon-alpha and a histone deacetylase inhibitor, sodium butyrate, on human liver cancer cell lines. In this study, invasive ability of human liver cancer cell lines through the matrix-coated membrane was examined and inhibitory effect of interferon-alpha and sodium butyrate was investigated. Among six human liver c...

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