The present study was designed to investigate the immunomodulatory activity of the ethanolic extract of Tinospora cordifolia (Family: Menispermaceae)stem (climbing shrub, mango plant) at cellular level. For antioxidant study, the liver mitochondria were separated and the concentration of enzymes like lipid peroxidation (LPO), reduced glutathione (GSH), catalase (CAT) and superoxide Dismutase (S...

BACKGROUND Atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed in blood vessels. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs have certain limitations which cause serious and sometimes fatal consequences. Herbal preparations have been used since ancient times for the t...

Background and ObjectivesTinospora cordifolia (Willd.) Miers ex Hook. f. & Thoms. (T. cordifolia) has been shown to be hepatoprotective by Ayurvedic physicians but has not been scientifically evaluated so far. So, the present study was undertaken to explore the hepatoprotective activity of T. cordifolia against experimentally induced hepatotoxicity in albino rats. Aim of The Study-To explore th...

OBJECTIVE Tinospora cordifolia is used for treatment of several diseases in Indian system of medicine. In the present study, the inhibition potential of T. cordifolia extracts and its constituent tinosporaside to cause herb-drug interactions through rat and human liver cytochrome enzymes was evaluated. MATERIALS AND METHODS Bioactive compound was quantified through reverse phase high-performa...

The present study was designed to investigate the immunomodulatory activity of the ethanolic extract of Tinospora cordifolia (Family: Menispermaceae) stem (climbing shrub, mango plant) at cellular level. For antioxidant study, the liver mitochondria were separated and the concentration of enzymes like lipid peroxidation (LPO), reduced glutathione (GSH), catalase (CAT) and superoxide Dismutase (...

The primary objective of this investigation is to determine the deleterious effects of sub lethal gamma radiation on testes and their possible inhibition by Tinospora cordifolia extract (TCE). For this purpose, one group of male Swiss albino mice was exposed to 7.5 Gy gamma radiation to serve as the irradiated control, while the other group received TCE (75 mg/kg b. wt./day) orally for 5 consec...

The present study was conducted to explore the adipogenic potential and glucose uptake stimulatory activity of Phyllanthus emblica and Tinospora cordifolia using 3T3L1 fibroblast cell line as pre-adipocytes.The plant extracts were substituted for insulin in the Insulin-IBMX-DEX cocktail used for differentiation of pre-adipocytes. The degree of differentiation of these plants was assessed by Oil...

Antibiotic resistance has become a global concern and hence, the search for other source of antimicrobials initiated to find way control infections in future. The main objective this paper is screen Giloy (Tinospora cordifolia) its antibacterial activity. stem Tinospora cordifolia used prepare extract determining it’s vitro activity as per agar well diffusion method. In method 100μl 24 hr broth...

Guduchi is a plant also known as Tinospora cordifolia, having heart shaped leave, an herb of the family Menispermaceae native hot areas Indian subcontinent. In our classical Ayurvedic texts, it indicated to be beneficial in treating various types diseases like skin disorders, different fever, jaundice & gout. claimed have properties anti-oxidant, antihyperglycemic, antihyperlipidemic, hepat...