We report on a patient with biopsy proven systemic Wegener's granulomatosis (WG) with a granulomatous necrotising manifestation of WG in the liver, lung, parotid gland and skin with subsequent death of liver failure. Liver involvement in WG is an exceedingly rare, though potentially fatal, organ manifestation of WG.

ESR: erythrocyte sedimentation rate INTRODUCTION Rosai-Dorfman disease, also called sinus histiocytosis with massive lymphadenopathy, is a rare histiocytic condition of unknown etiology first described in 1969. Primary cutaneous manifestation without systemic involvement of Rosai-Dorfman disease is even more uncommon. Here we present a case of primary cutaneous manifestation of Rosai-Dorfman di...

Scleroderma renal crisis has been documented as the presenting manifestation of systemic sclerosis sine scleroderma in pregnancy only once in the literature. Unfortunately, since scleroderma renal crisis in sine scleroderma pregnant patients is so rare, that patient expired. We present a case of a sine scleroderma pregnant patient with an initial manifestation of scleroderma renal crisis surviv...

INTRODUCTION Lupus cystitis is a rare manifestation of systemic lupus erythematosus, characterized by thickening of the bladder wall, associated with ureterohydronephrosis. In several cases gastrointestinal symptoms are the main manifestation. The optimal immunosuppressive regimen is still unknown. METHODS 16-year-old girl with systemic lupus erythematosus was admitted with dysuria, renal imp...

Uveitis is often a manifestation of sarcoidosis. Less well-recognized, however, is the development of uveitis several years before the diagnosis of systemic sarcoidosis. The possibility that presentation of uveitis is a marker for the chronicity of sarcoidosis has never been investigated. The aim of this work was to evaluate, in a Caucasian population, the epidemiology of uveitis as the primary...

We conducted a double-blind randomized placebo controlled trial to evaluate the impact of Lemon balm (Melissa officinalis L.) on the bleeding and systemic manifestations of menstruation. A total of 90 students were randomly assigned to treatment or placebo group. Bleeding and systemic manifestations were evaluated with a menstrual pictogram and multidimensional verbal scale before and during 2 ...

introduction: henoch schonlein purpura (hsp) is a self-limited systemic disease with multiorgan involvement. while cutaneous involvement may wary, presenting as itching papules is not a common manifestation. in this report we discuss a case of hsp which was presented solely with itching papules; mistaken for scabies. case presentation: a 7 year old boy presented with itchy palpable papules with...

Systemic lupus erythematosus (SLE) can involve many parts of the eye, including the eyelid, ocular adnexa, sclera, cornea, uvea, retina and optic nerve. Ocular manifestations of SLE are common and may lead to permanent blindness from the underlying disease or therapeutic side effects. Keratoconjunctivitis sicca is the most common manifestation. However, vision loss may result from involvement o...

Intuitively, dynamic visual stimuli, such as moving objects or flashing lights, attract attention. Visual search tasks have revealed that dynamic targets among static distractors can indeed efficiently guide attention. The present study shows that the reverse case, a static target among dynamic distractors, allows for relatively efficient selection in certain but not all cases. A static target ...

Background: While acute pruritus is often attributable to yeast vulvovaginitis, chronic pruritus can present as the result different conditions including manifestation of a systemic