The state of lipid peroxidation (LPO), respiration and oxidative phosphorylation, mitochondrial permeability transition pore (mPTP) antiradical activity rat liver mitochondria in streptozotocin (STZ)-induced diabetes condition were studied, considered the ways correction detected membrane damages with use gossitan, isolated from cotton plant Gossypium hirsutum L. It was shown that rate states V...

Low density lipoprotein (LDL) receptors are found in most cells, including adipose cells. LDL receptors are primarily regulated by cellular cholesterol content. Insulin and insulin deficiency have been reported to have varying effects on LDL receptors in various tissues. The present study was undertaken to assess the in vivo effects of streptozotocin-induced diabetes on LDL receptor expression ...

objective(s): this study was to investigate the potential anti-diabetic effects of alcoholic extract of salvia hydrangea in rats. materials and methods:thirty five male wistar rats were divided into five groups namely non-diabetic control, diabetic control, and three experimental diabetic that received either salvia hydrangea extract for 21 days at the doses of 100 and 200 or glibenclamide at t...

Polysaccharide –based hydro gels from marine algae are attractive materials for biomedical applications which include polyfunctionality and biodegradability. There were reports of many based hydrogels their in diabetic neuropathy. The present study aims to investigate the progressive effects injectable Chitosan-Ulva lactuca polysaccharide hydrogel (C-UL hydrogel) on experimentally induced neuro...

retina is a part of the central nervous system derived from the neuroectoderm and made up of 5 layers.in this study, the changes in the thickness of the retinal layers as a consequence of diabetes and effect of aloe vera gel extract in male rats were assessed. thirty sprague dawley adult male rats (175 ± 25 g) in two age groups (4 and 8 weeks) were divided into 6 groups of 5 as control, diabeti...

objective(s): diabetes mellitus is a public health problem and one of the five leading causes of death globally. in the present study, the effect of metformin with natural honey was investigated on glycemia in the streptozotocin-induced diabetic rats. materials and methods: thirty wistar male rats were randomly divided into six groups including c: non ­diabetic rats received distilled water, ch...

Diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. The objective of the present study was to evaluate the effect of aqueous extract of Cydonia oblonga Mill. Fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. The extract showed anti hyper lipidemic...

In this study, it was investigated of the effect Polygonum cognatum Meissn. ethanol extract Bax, Bcl-2, Caspase-3, NF-kB and NRF-2/HO-1 pathways in streptozotocin induced diabetic rats. A total 24 healthy Spraque-Dawley male rats were randomly divided into four groups containing 6 per group as Control; Diabetes mellitus (DM); (PCE) DM+PCE. Experimental diabetes by a single dose 60 mg/kg/i.p Str...

Background: Medicinal plants are used as alternative therapy for diabetes. This study investigated comparative effects of methanolic extracts Anacardium occidentale (linn) nut, leaf and stem bark on hyperglycemia associated abnormalities in streptozotocin-induced diabetic rats.
 Methods: Ninety male Wistar albino rats weighing (200±20g) were diabetes was induced by single intraperitoneal i...