When streptokinase is incubated with human or rabbit plasminogen, one event which occurs is a specific fragmentation of streptokinase. At least five major identifiable streptokinase fragments appear with time, and they possess molecular weights of approximately 40,000 (SK I), 36,000 (SK 2), 31,000 (SK 3), 26,000 (SK 4), and 10,000 (SK 5) under denaturing conditions, as observed on calibrated so...

This paper presents a solution to increase the throughput of an HF (High Frequency) physical (PHY) layer in particular to allow for services such as IP over HF. Additionally, this new PHY layer can improve the adaptability of the waveform to the channel variations, in particular to limit the retransmissions due to errors. Taking into consideration the existing HF spectrum occupancy and its high...

Biological Systems M. Jake Pushie,† Ingrid J. Pickering,†,‡,§ Malgorzata Korbas, Mark J. Hackett,† and Graham N. George*,†,‡,§ †Molecular and Environmental Sciences Research Group, Department of Geological Sciences, University of Saskatchewan, Saskatoon, SK S7N 5E2, Canada ‡Toxicology Centre, University of Saskatchewan, Saskatoon, SK S7N 5B3, Canada Department of Chemistry, University of Saskat...

Endothelial cells (ECs) regulate the barrier function of blood vessels. Here we show that basal and angiopoietin-1 (Ang-1)-regulated control of EC permeability is mediated by 2 different functional states of sphingosine kinase-1 (SK-1). Mice depleted of SK-1 have increased vascular leakiness, whereas mice transgenic for SK-1 in ECs show attenuation of leakiness. Furthermore, Ang-1 rapidly and t...

The efficacy of three different treatment protocols was compared: 1) simple chest tube drainage (Drain); 2) adjunctive intrapleural streptokinase (IP-SK); and 3) an aggressive empirical approach incorporating SK and early surgical drainage (SK+early OP) in patients with pleural empyema and high-risk parapneumonic effusions. This was a nonrandomized, prospective, controlled time series study of ...

By using the notions of exact truth (‘true and not false’) and exact falsity (‘false and not true’), one can give 16 distinct definitions of classical consequence. This paper studies the class of relations that results from these definitions in settings that are paracomplete, paraconsistent or both and that are governed by the (extended) Strong Kleene schema. Besides familiar logics such as Str...

Researchers on South Kyungsang Korean (SK) have been divided as to whether SK is a tone language or a pitch-accent language. While traditionally SK Korean has been viewed as a tone language (U Huh 1954, C-G Gim 1994, 1998, H-Y Lee 1994, 1997), there has been an alternative view that SK is a pitch-accent language (Ramsey 1974, 1975, JW Kim 1991, Kubozono 2007, DM Lee 2008). The split between the...