backgroud: protein-protein interaction, plays a key role in signal transduction in signaling pathways. different approaches are used for prediction of these interactions including experimental and computational approaches. in conventional node-edge protein-protein interaction networks, we can only see which proteins interact but ‘structural networks’ show us how these proteins interact which ca...

The response to drought stress is a complicated process involving stress sensing, intracellular signaltransduction, and the execution of a cellular response. Transcription factors play important roles in the signaling pathways including abiotic stress. In the present study a rice NF-YA transcription factor gene was partially characterized following dehydration. Disrupting the gene via a T...

Neuroinflammatory disorders include a wide spectrum of disorders in which immune system injures components of the nervous system. Despite the advances in therapy, lack of efficient curative therapies for these disorders not only affects the quality of life but also places huge burden on the society. These limitations have necessitated therapeutic interventions for developing more efficient regi...

Thromboangiitis obliterans (TAO) is a thrombotic-occlusive as well as an inflammatory peripheral vascular disease with unknown etiology. Recent evidence has supported the immunopathogenesis of the disease, however, the factors contributing to the altered immune function and vascular tissue inflammation are still unclear. This review was intended to collate the more current knowledge on the regu...