Fold designability has been estimated by the number of families contained in that fold. Here, we show that among orthologous proteins, sequence divergence is higher for folds with greater numbers of families. Folds with greater numbers of families also tend to have families that appear more often in the proteome and greater promiscuity (the number of unique "partner" folds that the fold is foun...

We give an explicit sequence of Heegaard moves interpolating between local versions the Kauffman-states diagram and planar used in knot Floer homology, show how these can be to translate global diagrams.

  Objective(s): Hypoxia is a serious challenge for treatment of solid tumors. This condition has been manifested to exert significant therapeutic effects on glioblastoma multiform or (WHO) astrocytoma grade IV. Hypoxia contributes numerous changes in cellular mechanisms such as angiogenesis, metastasis and apoptosis evasion. Furthermore, in molecular level, hypoxia can cause induction of DNA br...

boophilus genus ticks are responsible for transferring some pathogens and reducing production factors in cattle. tropomysin (tpm) protein has actin regulator activity and playing important role in immune and allergic reactions. the main goal is to determine different aspects of phylogenetic, similarity, homology, structure and allergenicity of tpm protein. in prior study, we identified tpm by u...

Tate local cohomology and Gorenstein theory, which are important generalizations of the classical cohomology, has been investigated. It found that they have such vanishing properties long exact sequences. However, for homology, what about duality? In this paper we concerned with homology homology. first part generalize as study properties, artinianness some sequence modules. We find an artiania...

This paper shows how homology modeling works for given protein sequence and how it is implemented in grid environment. Homology modeling involves taking a known sequence with an unknown structure and mapping against a known structure of one or several similar protein. The quality of homology modeling is dependent on the quality of the sequence alignment and template structure. Based on this mod...

κ-casein is a glycosilated protein belonging to a family of phosphoproteins (αs1,β, αs2,κ) that represents the major protein component in mammalian milk. κ-casein plays an essential role in the case of micelle stabilization, determining the size and the specific biological function. In the present study, we report the characterization of the partial sequence of κ-casein promoter region in the I...

κ-casein is a glycosilated protein belonging to a family of phosphoproteins (αs1,β, αs2,κ) that represents the major protein component in mammalian milk. κ-casein plays an essential role in the case of micelle stabilization, determining the size and the specific biological function. In the present study, we report the characterization of the partial sequence of κ-casein promoter region in the I...

Since 2005 a new powerful invariant of an algebra has emerged using the earlier work of Horvath, Hethelyi, Kulshammer and Murray. The authors studied Morita invariance of a sequence of ideals of the center of a nite dimensional algebra over a eld of nite characteristic. It was shown that the sequence of ideals is actually a derived invariant, and most recently a slightly modied version o...