Steroid 11β-hydroxylase (CYP11B1; EC 1.14.15.4) is a mitochondrial enzyme located in the zona fasciculata of the adrenal cortex and also in the brain that mediates the conversion of 11-deoxycortisol to cortisol and 11-deoxycorticosterone (DOC) to corticosterone. Inhibitors of CYP11B1, such as metyrapone and etomidate, reduce glucocorticoid synthesis and raise levels of DOC providing greater ava...

introduction: seizure is the most common pediatric neurology problem that occurs in 10% of children. the purpose of this study was to determine the recurrence rate of seizures after one year and its relationship with paraclinical findings of the first attack. methods : in a historical cohort analytic study , 131 children with first seizure admitted to shaheed sadoughi hospital between march 200...

The invertible, compact and Fredholm multiplication operators on generalized Lorentz-Zygmund (GLZ) spaces Lp,q;α, 1 < p ≤ ∞, 1 ≤ q ≤ ∞, α in the Euclidean space R, are characterized in this paper.

introduction: febrile seizure is the most common problem in pediatric neurology that occur s in 3– 4% of children. the purpose of this study was to evaluate demographic and clinical characteristics of first febrile seizures in children admitted to the hospital. methods: in a descriptive retrospective study, medical records of children with first febrile seizure, admitted between march 2004and a...

BACKGROUND Epilepsy is one common neurological disorder requiring newer targets and newer drugs for its efficient management. In the recent days brain renin angiotensin system has gained immense importance because of its involvement in seizure regulation. OBJECTIVE To evaluate and compare antiepileptic activity of different doses olmesartan and telmisartan on MES and PTZ induced seizure model...

how to cite this article: fallah r, tirandazi f, ferdosian f, fadavi n. iron deficiency and iron deficiency anemia in children with first attack of seizure and on healthy control group : a comparative study. iran j child neurol. 2014 summer;8(3): 18-23.   abstract objective seizures are the most common pediatric neurologic problem. research of the association between iron deficiency and seizure...

introduction: febrile seizure is the most common type of seizure that occurs in 3– 4% of children below the age of 5 years. the purpose of this study was to determine the frequency of recurrence of febrile and afebrile seizures after the first febrile seizure. methods: in a descriptive prospective study, 139 children (6months to 6years old) admitted between march 2004and august 2005 at yazd sha...

Background: Convulsion is a condition where in the muscles of the body contract and relaxes rapidly and repeatedly resulting in an uncontrolled shaking of the body .It is often a symptom of the epileptic seizure. Gap junctions play an important role in the generation and spread of the epileptic seizures .Quinidine being one of the gap junction blockermay have the potential role in the treatment...

Catamenial epilepsy is a type of refractory epilepsy characterized by seizure clusters around perimenstrual or periovulatory period. The pathophysiology of catamenial epilepsy still remains unclear, yet there are few animal models to study this gender-specific disorder. The pathophysiology of perimenstrual catamenial epilepsy involves the withdrawal of the progesterone-derived GABAergic neurost...