staphylococcus aureus are important factors for infections that acquired of hospital and community. infections caused by methicillin-resistant staphylococcus aureus mainly of hospital origin, which in many countries is increasing. for this reason, many researchers have tried to find new compounds as a substitute for these antibiotics. hypericin is the active substance h.perforatum and licone ma...

The increasing emergence of multiresistant bacteria in health care settings in the community and in the environment represents a major health threat worldwide. Here, we report the draft genome sequence of a community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) USA300 isolate (W1) from a small river in southern Austria.

tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. it has broad spectrum activity, including staphylococcus aureus infections. this is the first study that evaluated the activity of tigecycline against staphylococcus aureus isolated from biological samples in iran. in vitro activity of tigecycline against 160 staphylococcus aureus including 99 methicil...

conclusions these findings illustrated the presence and persistence of clonal groups of mrsa strains, in chicken meat in isfahan, iran, that serve as reservoirs to disseminate bacteriophage encoded enterotoxin and virulence agents. results all 116 isolated mrsa strains were discriminated into seven php types consisting of seven common types (cts) and were positive for meca gene. all isolates ha...

background coagulase-negative staphylococci (cons) are opportunistic pathogens. methicillin resistance is common in cons and may play an important role as reservoir of staphylococcal cassette chromosome mec (sccmec) for staphylococcus aureus. objectives the aim of this study was to determine molecular characteristics of nasal carriage of methicillin-resistant coagulase negative staphylococci am...

conclusions silver nanoparticles have high therapeutic activity against mrsa, thus can be suggested as an alternative or adjuvant with antibiotics for mrsa treatment. further studies are required to understand the synergistic effect of ag-nps combinations and to assess the safety and efficacy of new antibiotic-ag-nps combinations. background methicillin-resistant staphylococcus aureus (mrsa) ar...

background:   methicillin-resistant   staphylococcus   aureus  (mrsa)   is  a major cause of nosocomial and community infections that are becoming increasingly difficult to combat, because of emerging resistance to all classes of antibiotics. moreover panton-valentine  leukocidin (pvl) is an important virulence factor in s. aureus and causes white blood cell destruction, necrosis and  accelerat...

the plant kingdom constitutes a source of new chemical compounds, which may be important due to their potential uses in medicine, or their other biological properties. in this study, the effects of galbanic acid (ga), a sesquiterpene coumarin from roots of ferula szowitsiana, were investigated as a modulator of antibiotic resistance in clinical isolates of staphylococcus aureus. isolates of s. ...

OBJECTIVES Bactericidal activity depends on antibiotic-bacteria couples, resistance phenotype and theoretically on protein binding. This work explores the influence of protein binding on the bactericidal activity of two antibiotics, daptomycin versus vancomycin, that exhibit, respectively, different C(max) (56 versus 25.5 mg/L), protein binding (91.7% versus 36.9%) and thus theoretical free-dru...

background: methicillin-resistant staphylococcus aureus (mrsa) is resistant to most antibiotics and is an important pathogen of nosocomial infections. the prevalence of community (ca-mrsa) and hospital acquired methicillin-resistant s. aureus (ha-mrsa) infection is increased. in this study we investigated the frequency of mrsa colonization and its antibiotic susceptibility in students of rafsan...